| Extracapsular tumor extension in cervical lymph nodes: reconciling the literature and seer data. | |
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MedLine Citation:
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PMID: 20824808 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Extracapsular extension (ECE) of disease from cervical lymph nodes (LNs) is an important prognostic factor for head and neck cancers; moreover, the presence of ECE has been shown to be a criterion for the addition of chemotherapy to postoperative radiation. METHODS: We reviewed the frequency of ECE in the Surveillance, Epidemiology, and End Results (SEER) registry database, particularly as it related to nodal size. Our objective was to compare these findings with the literature. RESULTS: SEER data suggest that the likelihood of ECE does not increase linearly with LN size, whereas most reports in the literature suggest that the likelihood of ECE does increase with increasing LN size. CONCLUSIONS: SEER data and the literature are not consistent in describing the relationship between ECE and LN size. These results suggest the need for better standardization in the assessment and reporting of ECE. |
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Authors:
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Amber G Brannan; Peter A S Johnstone; Jay Cooper |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review Date: 2010-09-07 |
Journal Detail:
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Title: Head & neck Volume: 33 ISSN: 1097-0347 ISO Abbreviation: Head Neck Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-22 Completed Date: 2011-08-03 Revised Date: 2011-12-20 |
Medline Journal Info:
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Nlm Unique ID: 8902541 Medline TA: Head Neck Country: United States |
Other Details:
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Languages: eng Pagination: 525-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Wiley Periodicals, Inc. |
Affiliation:
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Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Head and Neck Neoplasms
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pathology* Humans Lymph Nodes / pathology* Lymphatic Metastasis* Neck SEER Program |
| Comments/Corrections | |
Comment In:
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Head Neck. 2011 Dec;33(12):1809
[PMID:
22006529
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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