| Extra hepatic portal vein obstruction and pregnancy outcome: Largest reported experience. | |
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MedLine Citation:
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PMID: 21375674 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Aim: Evaluate pregnancy outcome in women with extra hepatic portal vein obstruction (EHPVO). Material & Methods: A total of 26 pregnancies in 14 women with EHPVO were evaluated for maternal and perinatal outcomes in a tertiary centre of Northern India. Fourteen pregnancies were evaluated prospectively while the details of 12 previous pregnancies in the same women were studied retrospectively. Results: Mean age of pregnant women with EHPVO was 24.5 years and approximately one-third were primigravidae. Only one patient was diagnosed as EHPVO in the index pregnancy. The presenting event was hematemesis in 71% of the patients; others presented with thrombosis, pain abdomen and jaundice or incidental splenomegaly. The incidence of abortion, preterm deliveries and still births was 20%, 15.4% and 7.7%, respectively. Underlying hypercoagulable and prothrombotic state was diagnosed in around one-fifth of the patients. Half of these women required platelet transfusion in the intrapartum period due to hypersplenism resulting in thrombocytopenia. Anemia was seen in 40% of the patients; however, no other major complications were seen as a result of EHPVO. The vaginal delivery rate and obstetrical outcome were similar as in general population. Conclusion: Pregnancy outcome is expected to be successful in women with EHPVO if disease is adequately controlled prior to pregnancy. |
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Authors:
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Neelam Aggarwal; Seema Chopra; Ainharan Raveendran; Vanita Suri; Radha Krishan Dhiman; Yogesh Kumar Chawla |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-6 |
Journal Detail:
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Title: The journal of obstetrics and gynaecology research Volume: - ISSN: 1341-8076 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-7 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9612761 Medline TA: J Obstet Gynaecol Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 The Authors. Journal of Obstetrics and Gynaecology Research © 2011 Japan Society of Obstetrics and Gynecology. |
Affiliation:
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Departments of Obstetrics and Gynaecology Hepatology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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