Document Detail


Extra [corrected] pulmonary uptake of Tc-99m-MAA perfusion lung scan as a result of right to left intra cardiac shunt.
MedLine Citation:
PMID:  16767956     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Extra pulmonary accumulation of Tc-99m-macroaggregate of albumin (MAA) is rarely seen on perfusion lung scan, and has been reported in less than 4% of a study population of nearly 380 patients. It occurs when the agent bypasses the lungs due to a right to left (R-L) cardiac or pulmonary shunt, when it is shunted to the portal vein before reaching the right atrium and ventricle of the heart, and when the agent is degraded to a submicron particle size. When a pharmaceutical problem is excluded, extra-pulmonary uptake implies unusual hemodynamics with a shunt. A case is reported in which a clinically unsuspected shunt was diagnosed from the lung perfusion scintigraphy.
Authors:
Riffat Hussain; Maseeh-uz-Zaman; Sohail Abrar Khan; M Nadeem Ahmad
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  56     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-06-13     Completed Date:  2006-07-25     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  241-2     Citation Subset:  IM    
Affiliation:
Department of Radiology, Aga Khan University Hospital, Karachi.
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MeSH Terms
Descriptor/Qualifier:
Adult
Arteriovenous Fistula / physiopathology,  radionuclide imaging*
Female
Heart Atria / abnormalities
Heart Septal Defects, Atrial / physiopathology,  radionuclide imaging*
Humans
Hypertension, Pulmonary / etiology*
Lung / radionuclide imaging*
Perfusion*
Pulmonary Circulation*
Pulmonary Veins / abnormalities
Radiopharmaceuticals / diagnostic use*
Technetium Tc 99m Aggregated Albumin / diagnostic use*
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 0/Technetium Tc 99m Aggregated Albumin
Comments/Corrections
Erratum In:
J Pak Med Assoc. 2006 Jun;56(6):296

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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