Document Detail

Extra-amniotic prostaglandin E2 for midtrimester termination of pregnancy in live fetuses vs. fetal demise.
MedLine Citation:
PMID:  14504874     Owner:  NLM     Status:  MEDLINE    
This study compared the course of midtrimester termination of pregnancies with fetal demise and those with a viable fetuses by extra-amniotic prostaglandin (PG) E(2). A total of 275 women who underwent second trimester abortion with extra-amniotic PGE2(2) were divided into two groups: 95 patients (35%) with fetal demise and 180 women (65%) with a live fetuses. Extra-amniotic PGE2(2) was administered in doses of 200 micro g every 2 h up to 20 doses. Bumm curettage was performed in the majority of the patients. We compared the duration and complication rate between the groups. The median induction to abortion interval was significantly shorter in the fetal demise group (13 vs. 21 h) than in the live fetus group. Mean gestational ages and complication rates were similar. Midtrimester termination of pregnancy with extra-amniotic PGE2(2) is a safe method with a low complication rate. In cases of pregnancy with fetal demise extra-amniotic PGE2(2) is associated with a significantly shorter induction to abortion interval than with a live fetus.
A Debby; R Sagiv; O Girtler; O Sadan; M Glezerman; A Golan
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2002-09-05
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  268     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-09-23     Completed Date:  2004-02-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  301-3     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Sacker Faculty of Medicine, Tel Aviv University, Holon 58100, Tel Aviv, Israel.
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MeSH Terms
Abortion, Induced / adverse effects,  methods*
Dinoprostone / administration & dosage*,  adverse effects
Fetal Death*
Gestational Age*
Oxytocin / administration & dosage
Pregnancy Trimester, Second
Time Factors
Reg. No./Substance:
363-24-6/Dinoprostone; 50-56-6/Oxytocin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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