Document Detail

External ophthalmoplegia after total intravenous anaesthesia.
MedLine Citation:
PMID:  8017599     Owner:  NLM     Status:  MEDLINE    
Eye-opening and eye movements were assessed in 110 awake and cooperative ASA class 1 and 2 patients after elective ENT surgery with total intravenous anaesthesia using propofol, fentanyl and atracurium. Following tracheal extubation and after regaining consciousness 21 patients showed a complete transient bilateral inability to open their eyes combined with a total gaze paresis, while another 30 patients showed an impairment of eye-opening and/or eye movements to a lesser extent. In all patients affected symmetrical recovery of both impaired eye-opening and eye movements occurred during the following 20 min. The occurrence of ophthalmological symptoms was not related to the duration of anaesthesia or the propofol infusion rate. Thus a complex ophthalmological phenomenon occurred after total intravenous anaesthesia in approximately 50% of awake and cooperative patients. The aetiology of this phenomenon and the implications for the understanding of the mechanisms of general anaesthesia remain to be determined.
S C Marsch; H G Schaefer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  49     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1994 Jun 
Date Detail:
Created Date:  1994-07-25     Completed Date:  1994-07-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  525-7     Citation Subset:  AIM; IM    
Department of Anaesthesia, Kantonsspital, Basel, Switzerland.
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MeSH Terms
Anesthesia Recovery Period
Anesthesia, Intravenous / adverse effects*
Eye Movements
Ophthalmoplegia / chemically induced*
Postoperative Complications / chemically induced*
Propofol / administration & dosage,  adverse effects*
Prospective Studies
Time Factors
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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