| Extent to which accepted serum lipid goals are achieved in a contemporary general medical population with coronary heart disease risk equivalents. | |
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MedLine Citation:
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PMID: 17056335 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study examined lipid levels and the use of lipid-altering drugs in a contemporary general medical population without documented coronary heart disease (CHD) but with CHD risk equivalents. On the basis of present national guidelines, the following lipid values (in milligrams per deciliter) were considered optimal for this population: low-density lipoprotein cholesterol <100, high-density lipoprotein (HDL) cholesterol >or=40 in men and >or=50 in women, and non-HDL cholesterol <130 if triglycerides are >or=200. Of 44,052 active patients screened, 877 with CHD risk equivalents as defined by the Adult Treatment Panel III guidelines were identified. Most patients did not meet optimal lipid targets for low-density lipoprotein cholesterol (59%), HDL cholesterol (66%), and non-HDL cholesterol (72%). Indeed, 88% of patients did not meet >or=1 lipid goal. Statins were used in 57% of patients. In patients with low HDL cholesterol, only 4.7% were taking niacin and 4.9% fibrates. In the subgroup of patients with triglycerides >or=200 mg/dl, only 9.5% were taking fibrates and 8.2% niacin. In conclusion, the present analysis highlights the dramatic need to further improve preventive measures in a substantial proportion of high-risk patients with CHD risk equivalents. |
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Authors:
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Alawi A Alsheikh-Ali; Jen-Liang Lin; Paul Abourjaily; Dineli Ahearn; Jeffrey T Kuvin; Richard H Karas |
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Publication Detail:
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Type: Journal Article Date: 2006-09-07 |
Journal Detail:
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Title: The American journal of cardiology Volume: 98 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2006 Nov |
Date Detail:
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Created Date: 2006-10-23 Completed Date: 2006-12-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1231-3 Citation Subset: AIM; IM |
Affiliation:
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Division of Cardiology and Molecular Cardiology Research Institute, Tufts-New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antilipemic Agents / therapeutic use Biological Markers / blood Cholesterol, HDL / blood, drug effects Cholesterol, LDL / blood, drug effects Coronary Disease / blood*, epidemiology*, etiology, prevention & control Dyslipidemias / blood, complications, drug therapy, epidemiology Female Goals* Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use Lipids / blood* Male Middle Aged Risk Assessment Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Antilipemic Agents; 0/Biological Markers; 0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors; 0/Lipids |
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