| Extent of intra-arterial calcification on head CT is predictive of the degree of intracranial atherosclerosis on digital subtraction angiography. | |
| | |
MedLine Citation:
|
PMID: 19468214 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Intracranial intra-arterial calcifications (ICAC) are a common finding on head CT examinations, but their significance is not known. The aim of this study is to determine if a relationship exists between ICAC on head CT and the presence of a high-grade atherosclerotic stenosis on cerebral angiography. METHODS: This was a retrospective study of 108 consecutive patients admitted to the stroke service at Parkland Hospital in Dallas, Tex., USA. Each patient had undergone a head CT and catheter-based angiographic study to meet the inclusion criteria. Demographic information was recorded along with CT imaging data in regards to the amount of calcification. Angiographic images were reviewed independently, and a comparison was made to determine if calcification was predictive of finding a high-grade stenosis on angiography. RESULTS: A total of 108 consecutive patients with a mean age of 56 +/- 12 years were studied. Of the 540 vessels studied, 65 (12%) were found to have a stenosis of >or=50% on angiography, and 71 (13.1%) were found to have a calcium grade of 3 or 4 on head CT. ICAC appeared to be more common in the anterior circulation compared to the posterior circulation. Patients with grade 3 or 4 calcification of an intracranial vessel on head CT were more likely to have a stenosis of >or=50% on cerebral angiography. CONCLUSIONS: The presence of ICAC on head CT appears to correlate with the presence of an underlying intracranial stenosis on angiography. Further study is required to validate these preliminary findings. |
| | |
Authors:
|
Mounzer Y Kassab; Rishi Gupta; Arshad Majid; Muhammad U Farooq; Brian P Giles; Mark D Johnson; Dion F Graybeal; George Rappard |
Related Documents
:
|
12435934 - Noninvasive diagnosis of blunt cerebrovascular injuries: a preliminary report. 11958414 - Three-dimensional computed tomographic angiography with low loads of contrast agent in ... 2718864 - Mr imaging of intracranial carotid occlusion. 22250714 - Magnetic resonance imaging enhancement of intervertebral disc disease in 30 dogs follow... 22517104 - Simultaneous pml-iris after discontinuation of natalizumab in a patient with ms. 15549524 - Headache and intracranial hypotension: neuroradiological findings. |
Publication Detail:
|
Type: Journal Article Date: 2009-05-20 |
Journal Detail:
|
Title: Cerebrovascular diseases (Basel, Switzerland) Volume: 28 ISSN: 1421-9786 ISO Abbreviation: Cerebrovasc. Dis. Publication Date: 2009 |
Date Detail:
|
Created Date: 2009-06-23 Completed Date: 2009-09-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9100851 Medline TA: Cerebrovasc Dis Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 45-8 Citation Subset: IM |
Copyright Information:
|
(c) 2009 S. Karger AG, Basel. |
Affiliation:
|
Division of Cerebrovascular Diseases, Michigan State University and Sparrow Health System, East Lansing, MI 48824, USA. mounzer.kassab@ht.msu.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Angiography, Digital Subtraction Calcinosis / radiography* Cohort Studies Constriction, Pathologic / radiography Female Humans Intracranial Arterial Diseases / radiography* Intracranial Arteriosclerosis / radiography* Male Middle Aged Predictive Value of Tests Retrospective Studies Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The chelonian spinal nerve ganglia are a conglomerate of the spinal nerve ganglia proper and the sym...
Next Document: Diffusion-weighted imaging showing 'pearls' predicts large-vessel disease as stroke etiology.