Document Detail


Extensive chromoblastomycosis caused by Fonsecaea pedrosoi successfully treated with a combination of amphotericin B and itraconazole.
MedLine Citation:
PMID:  18324498     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chromoblastomycosis is a chronic infection caused by dematiaceous (dark-colored) fungi which affect the skin and subcutaneous tissues, and is characterized by a wide variety of clinical and dermatological features including papillomatous, verrucous and vegetating lesions. Although it has been described world-wide, most cases originate in tropical and sub-tropical areas. In general, present treatments of the disease are unsatisfactory as one of the most common etiologic agents, Fonsecaea pedrosoi is difficult to manage from a therapeutic point of view. We report a case of extensive chromoblastomycosis of 22 years duration caused by F. pedrosoi and review the clinical course, diagnosis and management of this disease.
Authors:
A-E Paniz-Mondolfi; M-T Colella; D-C Negrín; N Aranzazu; M Oliver; O Reyes-Jaimes; A-M Pérez-Alvarez
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Medical mycology     Volume:  46     ISSN:  1369-3786     ISO Abbreviation:  Med. Mycol.     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-07     Completed Date:  2008-08-13     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  9815835     Medline TA:  Med Mycol     Country:  England    
Other Details:
Languages:  eng     Pagination:  179-84     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Amphotericin B / adverse effects,  therapeutic use
Antifungal Agents / adverse effects,  therapeutic use*
Ascomycota / isolation & purification,  pathogenicity*
Chromoblastomycosis / drug therapy,  etiology*,  pathology
Drug Therapy, Combination
Humans
Itraconazole / adverse effects,  therapeutic use
Male
Mitosporic Fungi
Chemical
Reg. No./Substance:
0/Antifungal Agents; 304NUG5GF4/Itraconazole; 7XU7A7DROE/Amphotericin B

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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