Document Detail


Extended follow-up of the standard Hancock porcine bioprosthesis.
MedLine Citation:
PMID:  1810544     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have reviewed 665 patients in whom the standard Hancock porcine bioprosthesis (HPB) was used for aortic (AVR = 173), mitral (MVR = 437), and mitral and aortic (MAVR = 55) valve replacement in the time interval from 1970 to 1983. After AVR, HPB-related deaths occurred in 24 patients (1.7% +/- 0.4% per patient-year); 11 had thromboembolic episodes (0.8% +/- 0.2% per patient-year), 6 hemorrhages related to anticoagulants (0.4% +/- 0.2% per patient-year), 9 endocarditis (0.7% +/- 0.2% per patient-year), 7 prosthetic leak (0.5% +/- 0.1% per patient-year), and 59 structural deterioration (4.3% +/- 0.6% per patient-year). At 16 years, actuarial survival is 40% +/- 6%, freedom from thromboembolic episodes 89% +/- 4%, from hemorrhages 90% +/- 5%, from endocarditis 94% +/- 2%, from prosthetic leak 95% +/- 2%, and from structural deterioration 36% +/- 6%. After MVR, HPB-related deaths occurred in 64 patients (1.6% +/- 0.2% per patient-year); 68 had thromboembolic episodes (1.7% +/- 0.2% per patient-year), 28 hemorrhages (0.7% +/- 0.1% per patient-year), 12 endocarditis (0.3% +/- 0.1% per patient-year), 9 prosthetic leak (0.2% +/- 0.1% per patient-year), and 158 structural deterioration (4.0% +/- 0.3% per patient-year). At 18 years, actuarial survival is 33% +/- 4%, freedom from thromboembolic episodes 57% +/- 13%, from hemorrhages 81% +/- 6%, from endocarditis 91% +/- 4%, from prosthetic leak 98% +/- 1%, and from structural deterioration 18% +/- 5%.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
U Bortolotti; A Milano; A Mazzucco; F Guerra; L Testolin; G Thiene; V Gallucci
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  6     ISSN:  0886-0440     ISO Abbreviation:  J Card Surg     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-06-03     Completed Date:  1992-06-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  544-9     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Surgery, University of Padova Medical School, Italy.
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MeSH Terms
Descriptor/Qualifier:
Actuarial Analysis
Adolescent
Adult
Aged
Aortic Valve
Bioprosthesis*
Child
Female
Follow-Up Studies
Heart Valve Prosthesis / adverse effects*,  mortality
Humans
Male
Middle Aged
Mitral Valve
Reoperation
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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