| Expression of viral p21ras during acquisition of a transformed phenotype by rat adrenal cortex cells infected with Kirsten murine sarcoma virus. | |
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MedLine Citation:
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PMID: 3023835 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Rat adrenal cortex cells infected with Kirsten murine sarcoma virus acquire a transformed phenotype in a progressive fashion. The expression of the viral p21ras does not appear to correlate with the degree of transformation of the adrenocortical cells but rather is produced at similar levels as the culture becomes transformed. This indicates that the expression of an oncogenic form of p21ras is not of itself sufficient to completely transform rat adrenal cortex cells. |
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Authors:
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A MacAuley; N Auersperg; T Pawson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Molecular and cellular biology Volume: 6 ISSN: 0270-7306 ISO Abbreviation: Mol. Cell. Biol. Publication Date: 1986 Jan |
Date Detail:
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Created Date: 1987-01-16 Completed Date: 1987-01-16 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 8109087 Medline TA: Mol Cell Biol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 342-6 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex
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cytology,
metabolism* Animals Cell Transformation, Neoplastic* Cells, Cultured Genes* Genes, Viral* Kinetics Kirsten murine sarcoma virus / genetics* Mice Oncogene Protein p21(ras) Oncogene Proteins, Viral / genetics* Phenotype Rats Sarcoma Viruses, Murine / genetics* |
| Chemical | |
Reg. No./Substance:
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0/Oncogene Proteins, Viral; EC 3.6.5.2/Oncogene Protein p21(ras) |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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