Document Detail


Expression of transforming growth factor beta 2 RNA during murine embryogenesis.
MedLine Citation:
PMID:  2485246     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have studied the temporal and spatial expression of transforming growth factor beta 2 (TGF beta 2) RNA in mouse embryos from 10.5 days post coitum (p.c.) to 3 days post partum (p.p.) by in situ hybridization analysis. TGF beta 2 RNA is expressed in a variety of tissues including bone, cartilage, tendon, gut, blood vessels, skin and fetal placenta, and is in general found in the mesenchymal component of these tissues. The expression of TGF beta 2 RNA changes during development in a manner consistent with a role for the gene product in mediating mesenchymal-epithelial interactions.
Authors:
R W Pelton; S Nomura; H L Moses; B L Hogan
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Development (Cambridge, England)     Volume:  106     ISSN:  0950-1991     ISO Abbreviation:  Development     Publication Date:  1989 Aug 
Date Detail:
Created Date:  1993-03-16     Completed Date:  1993-03-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8701744     Medline TA:  Development     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  759-67     Citation Subset:  IM    
Affiliation:
Department of Cell Biology, Vanderbilt School of Medicine, Nashville, TN 37232.
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MeSH Terms
Descriptor/Qualifier:
Animals
Embryo, Mammalian / cytology,  physiology*
Embryonic and Fetal Development*
Female
Gestational Age
In Situ Hybridization
Male
Mice
Mice, Inbred ICR
Mice, Inbred Strains
Organ Specificity
RNA / analysis,  metabolism*
Transforming Growth Factor beta / biosynthesis,  genetics*
Grant Support
ID/Acronym/Agency:
CA 42572/CA/NCI NIH HHS; T32-GM07347/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Transforming Growth Factor beta; 63231-63-0/RNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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