Document Detail


Expression of a mitochondrial gene orfH79 from the CMS-HongLian rice inhibits Saccharomyces cerevisiae growth and causes excessive ROS accumulation and decrease in ATP.
MedLine Citation:
PMID:  19039529     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cytoplasmic male sterility (CMS) has often been associated with abnormal mitochondrial open reading frames (ORF), orfH79 is a mitochondria chimeric gene being responsible for the CMS trait in Honglian (HL) rice. Weakly expressed ORFH79 strongly inhibits the growth of yeast cells. In addition, the content of reactive oxygen species (ROS) in the transformants that expressed ORFH79 was increased by 31%, and ATP was decreased by 41% compared with the control. These results showed ORFH79 peptide is toxic to yeast cells.
Authors:
Xiaojue Peng; Fanhui Li; Shaoqing Li; Yingguo Zhu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-11-28
Journal Detail:
Title:  Biotechnology letters     Volume:  31     ISSN:  1573-6776     ISO Abbreviation:  Biotechnol. Lett.     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-02-02     Completed Date:  2009-02-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008051     Medline TA:  Biotechnol Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  409-14     Citation Subset:  IM    
Affiliation:
Key Laboratory of MOE for Plant Developmental Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei, 430072, China.
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MeSH Terms
Descriptor/Qualifier:
Adenosine Triphosphate / metabolism*
Cloning, Molecular
Gene Expression
Mitochondrial Proteins / genetics,  toxicity*
Oryza sativa / genetics*
Plant Proteins / genetics,  toxicity*
Reactive Oxygen Species / metabolism*
Recombinant Proteins / genetics,  toxicity
Saccharomyces cerevisiae / genetics,  growth & development*
Chemical
Reg. No./Substance:
0/Mitochondrial Proteins; 0/Plant Proteins; 0/Reactive Oxygen Species; 0/Recombinant Proteins; 56-65-5/Adenosine Triphosphate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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