Document Detail


Expression of heat-shock protein 70 (Hsp70) in the respiratory tract and lungs of fire victims.
MedLine Citation:
PMID:  16779550     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Immunohistochemical investigation of the respiratory tract and lungs of 63 fire victims revealed a statistically significant enhanced expression of heat-shock protein 70 (Hsp70) in the epiglottis, the trachea, and the main and the peripheral bronchi compared with a control group. In the fire victims, a strong expression of Hsp70 was discernible not only particularly in the vessels but also in seromucous secretory cells, ciliated epithelial cells, smooth muscle cells, and alveolar cells. The results suggest a vital or supravital reaction due to the inhalation of hot fire fumes.
Authors:
S Marschall; M A Rothschild; M Bohnert
Publication Detail:
Type:  Journal Article     Date:  2006-05-31
Journal Detail:
Title:  International journal of legal medicine     Volume:  120     ISSN:  0937-9827     ISO Abbreviation:  Int. J. Legal Med.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-24     Completed Date:  2007-06-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9101456     Medline TA:  Int J Legal Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  355-9     Citation Subset:  IM    
Affiliation:
Institute of Legal Medicine, Albert Ludwig University, Albertstrasse 9, 79104 Freiburg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Case-Control Studies
Child
Cilia / metabolism
Cytoplasm / metabolism
Endothelial Cells / metabolism
Epithelial Cells / metabolism
Female
Fires*
Forensic Pathology
HSP70 Heat-Shock Proteins / metabolism*
Humans
Immunohistochemistry
Lung / cytology,  metabolism*
Macrophages / metabolism
Male
Middle Aged
Myocytes, Smooth Muscle / metabolism
Respiratory System / cytology,  metabolism*
Serous Membrane / cytology,  metabolism
Smoke Inhalation Injury / metabolism
Chemical
Reg. No./Substance:
0/HSP70 Heat-Shock Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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