Document Detail


Expression of e-selectin in the skin of patients with atopic dermatitis: morphometric study.
MedLine Citation:
PMID:  20887694     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Adhesion molecules may play an important role in the homing of T-cell subsets into allergen-exposed skin of atopic individuals. The aim of this study was to examine the expression of adhesion molecules in atopic dermatitis skin lesions. Biopsies were obtained from lesions in 30 adult patients with atopic dermatitis and 10 healthy adults as controls. Biopsy specimens were studied by immunohistochemistry for the expression of E-selectin in epidermis and dermis cells. Results showed significant changes in the epithelial cell expression of E-selectin, which were especially pronounced in vascular endothelium of the dermis of atopic dermatitis patients.
Authors:
Sandra Marinović Kulišić; Jasna Lipozenčić; Gordana Gregorović; Gordana Gregurek; Gordana Lacković; Gordana Jurić-Lekić
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta dermatovenerologica Croatica : ADC     Volume:  18     ISSN:  1847-6538     ISO Abbreviation:  Acta Dermatovenerol Croat     Publication Date:  2010  
Date Detail:
Created Date:  2010-10-04     Completed Date:  2011-01-25     Revised Date:  2012-08-31    
Medline Journal Info:
Nlm Unique ID:  9433781     Medline TA:  Acta Dermatovenerol Croat     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  141-5     Citation Subset:  IM    
Affiliation:
University Hospital Center Zagreb, Department of Dermatology and Venereology, School of Medicine, University of Zagreb, Šalata 4, Zagreb, Croatia. sandra.marinovic@zg.htnet.hr
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy
Dermatitis, Atopic / metabolism*,  pathology
Dermis / metabolism
E-Selectin / metabolism*
Endothelium, Vascular / metabolism
Epidermis / metabolism
Humans
Immunohistochemistry
Middle Aged
Skin / metabolism*,  pathology
Chemical
Reg. No./Substance:
0/E-Selectin
Comments/Corrections
Erratum In:
Acta Dermatovenerol Croat. 2010 Dec;18(4):260
Note: Gregurek, Gordana [corrected to Gregorović, Gordana]

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