Document Detail

Exposure to lead from a storage site associated with intellectual impairment in Chilean children living nearby.
MedLine Citation:
PMID:  22069929     Owner:  NLM     Status:  In-Process    
This study assesses the degree of impairment of children's IQ scores due to exposure to lead from a storage site. In 2005, we studied 192 children in Antofagasta, Chile, age 7-16 years who had been exposed to a lead storage site from birth until its removal in 1998. We used past (1998) and current (2005) blood lead levels as explanatory variables for IQ, which was measured once in 2005 using the WISC-r test. Multilevel mixed-effects linear regression models were constructed, adjusting for potential confounders. Current blood lead level (BPb, 2005) was associated with a significant decrease in full-scale IQ (P value = 0.03), whereas blood lead level measured in 1998 (BPb, 1998) showed an inverse but not significant association with full-scale IQ (P value = 0.35). The findings provide evidence that exposure to an open source of environmental lead can exert an effect on IQ. Policy efforts should be targeted to prevent lead exposure to avoid children's intellectual impairment.
Veronica Iglesias; Kyle Steenland; Mildred Maisonet; Paulina Pino
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  International journal of occupational and environmental health     Volume:  17     ISSN:  1077-3525     ISO Abbreviation:  Int J Occup Environ Health     Publication Date:    2011 Oct-Dec
Date Detail:
Created Date:  2011-11-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505217     Medline TA:  Int J Occup Environ Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  314-21     Citation Subset:  IM    
School of Public Health, Faculty of Medicine, University of Chile, Chile.
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MeSH Terms
Grant Support
D43TW005746-02/TW/FIC NIH HHS

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