Document Detail


Exposure to influenza epidemics during gestation and adult schizophrenia. A 40-year study.
MedLine Citation:
PMID:  2393346     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We attempted to replicate earlier findings of an association between exposure to influenza in the second trimester of gestation and adult schizophrenia. The number of live births, of births of future schizophrenics, and of cases of influenza reported to the Ministry of Health in Denmark was ascertained by month from 1911 to 1950. The relationship between fetal exposure to influenza and adult schizophrenia was examined. It is possible that unknown factors produce excesses of both influenza and schizophrenia in the winter, creating an artifactual association. To control for this coincidence, the effects of season were removed from the monthly influenza and schizophrenic birth-rates by several methods. Using the residual scores, it was found that influenza rates higher than seasonally expected, occurring in the sixth month of gestation, were associated with rates of births of schizophrenics greater than seasonally expected. This association was not attributable to some winter-related, third factor or to climatic variables.
Authors:
C E Barr; S A Mednick; P Munk-Jorgensen
Related Documents :
21293866 - Seasonal variation of hypertrophic pyloric stenosis: a population-based study.
1430246 - Technical note: is there a season for iodinating relaxin?
7994506 - Low birth weight and schizophrenia.
8321156 - Discrimination between two competing hypotheses on seasonality of birth in subfecundabi...
21907256 - Impact of birth weight at term on rates of emergency room visits and hospital admission...
9397566 - A killing of baby doe.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of general psychiatry     Volume:  47     ISSN:  0003-990X     ISO Abbreviation:  Arch. Gen. Psychiatry     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-10-03     Completed Date:  1990-10-03     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372435     Medline TA:  Arch Gen Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  869-74     Citation Subset:  AIM; IM    
Affiliation:
Social Science Research Institute, University of Southern California, Los Angeles 90089-1111.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Birth Rate
Denmark / epidemiology
Disease Outbreaks / statistics & numerical data
Female
Finland / epidemiology
Gestational Age
Humans
Incidence
Infant, Newborn
Influenza, Human / complications*
Male
Pregnancy
Pregnancy Complications, Infectious / epidemiology*
Schizophrenia / diagnosis,  epidemiology,  etiology*
Scotland / epidemiology
Seasons
Grant Support
ID/Acronym/Agency:
5R01 MH37092/MH/NIMH NIH HHS; 5R01 MH37692/MH/NIMH NIH HHS; KO5-MH00619/MH/NIMH NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Changes in mood, craving, and sleep during short-term abstinence reported by male cocaine addicts. A...
Next Document:  An anti-human eosinophil monoclonal antibody AE500 that reacts only with granulocytes from hypereosi...