| Exposure to high dosage trihexyphenidyl during pregnancy for treatment of generalized dystonia: case report and literature review. | |
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MedLine Citation:
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PMID: 22045287 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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INTRODUCTION: : Trihexyphenidyl is 1 of the most effective agents for treatment of young-onset dystonia. As such, women of childbearing potential use trihexyphenidyl despite inadequate information about potential effects on pregnancy, labor, and fetal development. CASE REPORT: : We report 2 uncomplicated pregnancies in 1 woman with early-onset, sporadic, primary generalized dystonia (DYT1 negative) treated with high dosage trihexyphenidyl and review the literature on antidystonic agents and pregnancy. CONCLUSION: : Although there is limited data, our case demonstrates that high-dosage trihexyphenidyl treatment is not necessarily a contraindication to pregnancy. |
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Authors:
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Bradley James Robottom; Stephen G Reich |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The neurologist Volume: 17 ISSN: 1074-7931 ISO Abbreviation: Neurologist Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9503763 Medline TA: Neurologist Country: United States |
Other Details:
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Languages: eng Pagination: 340-1 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Maryland School of Medicine, Baltimore, MD. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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