Document Detail


Exposure stratified case-cohort designs.
MedLine Citation:
PMID:  10763560     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A variant of the case-cohort design is proposed for the situation in which a correlate of the exposure (or prognostic factor) of interest is available for all cohort members, and exposure information is to be collected for a case-cohort sample. The cohort is stratified according to the correlate, and the subcohort is selected by stratified random sampling. A number of possible methods for the analysis of such exposure stratified case-cohort samples are presented, some of their statistical properties developed, and approximate relative efficiency and optimal allocation to the strata discussed. The methods are compared to each other, and to randomly sampled case-cohort studies, in a limited computer simulation study. We found that all of the proposed analysis methods performed well and were more efficient than a randomly sampled case-cohort study.
Authors:
O Borgan; B Langholz; S O Samuelsen; L Goldstein; J Pogoda
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Lifetime data analysis     Volume:  6     ISSN:  1380-7870     ISO Abbreviation:  Lifetime Data Anal     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-05-23     Completed Date:  2000-05-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9516348     Medline TA:  Lifetime Data Anal     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  39-58     Citation Subset:  IM    
Affiliation:
Department of Mathematics, University of Oslo, Norway. borgan@math.uio.no
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MeSH Terms
Descriptor/Qualifier:
Biometry
Case-Control Studies*
Cohort Studies*
Humans
Likelihood Functions
Proportional Hazards Models
Research Design
Sampling Studies
Survival Analysis
Grant Support
ID/Acronym/Agency:
CA42949/CA/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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