| Exposure of infants to fumonisins in maize-based complementary foods in rural Tanzania. | |
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MedLine Citation:
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PMID: 18837467 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Feeding children with maize may expose them to fumonisins (FBs). This study assessed FB exposure for infants consuming maize in Tanzania by modeling maize consumption data (kg/kg body weight (bw)/day) with previously collected total FB contamination (microg/kg) patterns for sorted and unsorted maize harvested in 2005 and 2006. Consumption was estimated by twice conducting a 24 h dietary recall for 254 infants. The exposure assessment was performed with the @RISK analysis software. Of the infants, 89% consumed maize from 2.37 to 158 g/person/day (mean; 43 g/person/day +/- 28). Based on the contamination for sorted maize; in 2005, the percentage of infants with FB exposures above the provisional maximum tolerable daily intake (PMTDI) of 2 microg/kg (bw) (26% (95% confidence interval (CI); 23-30)) was significantly higher than the level of 3% (90% CI; 2-12) in 2006. Pooling the datasets for sorted maize from the two seasons resulted in a seemingly more representative risk (10% (95% CI; 6-17)) of exceeding the PMTDI. However, infants who might have consumed unsorted maize would still be at a significantly higher risk (24% (95% CI; 15-34)) of exceeding the PMTDI. Sorting and other good maize management practices should be advocated to farmers in order to minimize FB exposure in rural areas. |
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Authors:
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Martin E Kimanya; Bruno De Meulenaer; Katleen Baert; Bendantunguka Tiisekwa; John Van Camp; Simbarashe Samapundo; Carl Lachat; Patrick Kolsteren |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Molecular nutrition & food research Volume: 53 ISSN: 1613-4133 ISO Abbreviation: Mol Nutr Food Res Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-12 Completed Date: 2009-07-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101231818 Medline TA: Mol Nutr Food Res Country: Germany |
Other Details:
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Languages: eng Pagination: 667-74 Citation Subset: IM |
Affiliation:
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Tanzania Food and Drugs Authority, Dar es Salaam, Tanzania. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Food Contamination* Fumonisins / administration & dosage, toxicity* Humans Infant Maximum Tolerated Dose Tanzania Zea mays* |
| Chemical | |
Reg. No./Substance:
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0/Fumonisins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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