Document Detail

Exposure of infants to fumonisins in maize-based complementary foods in rural Tanzania.
MedLine Citation:
PMID:  18837467     Owner:  NLM     Status:  MEDLINE    
Feeding children with maize may expose them to fumonisins (FBs). This study assessed FB exposure for infants consuming maize in Tanzania by modeling maize consumption data (kg/kg body weight (bw)/day) with previously collected total FB contamination (microg/kg) patterns for sorted and unsorted maize harvested in 2005 and 2006. Consumption was estimated by twice conducting a 24 h dietary recall for 254 infants. The exposure assessment was performed with the @RISK analysis software. Of the infants, 89% consumed maize from 2.37 to 158 g/person/day (mean; 43 g/person/day +/- 28). Based on the contamination for sorted maize; in 2005, the percentage of infants with FB exposures above the provisional maximum tolerable daily intake (PMTDI) of 2 microg/kg (bw) (26% (95% confidence interval (CI); 23-30)) was significantly higher than the level of 3% (90% CI; 2-12) in 2006. Pooling the datasets for sorted maize from the two seasons resulted in a seemingly more representative risk (10% (95% CI; 6-17)) of exceeding the PMTDI. However, infants who might have consumed unsorted maize would still be at a significantly higher risk (24% (95% CI; 15-34)) of exceeding the PMTDI. Sorting and other good maize management practices should be advocated to farmers in order to minimize FB exposure in rural areas.
Martin E Kimanya; Bruno De Meulenaer; Katleen Baert; Bendantunguka Tiisekwa; John Van Camp; Simbarashe Samapundo; Carl Lachat; Patrick Kolsteren
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Molecular nutrition & food research     Volume:  53     ISSN:  1613-4133     ISO Abbreviation:  Mol Nutr Food Res     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-12     Completed Date:  2009-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231818     Medline TA:  Mol Nutr Food Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  667-74     Citation Subset:  IM    
Tanzania Food and Drugs Authority, Dar es Salaam, Tanzania.
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MeSH Terms
Food Contamination*
Fumonisins / administration & dosage,  toxicity*
Maximum Tolerated Dose
Zea mays*
Reg. No./Substance:

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