Document Detail


Exposure assessment: recommendations for nanotechnology-based pesticides.
MedLine Citation:
PMID:  21222390     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Given the development of nanotechnology within numerous scientific disciplines, it is likely that nanoscale products have been and will be used for agricultural, vector, and urban pest control prior to a complete evaluation of exposure and risk. Significant differences may exist between nanotechnology-based pesticides (NBPs) and conventional pesticides, primarily due to size and surface characteristics. These differences may result in changes in bioavailability, sensitivity, dosimetry, and pharmacokinetics. This paper considers the role of exposure assessment in the regulation of NBPs. While the existing regulatory infrastructure for pesticides is well established, several issues specific to NBP exposure are discussed, including: (1) disclosures of nanoparticle characteristics in product formulations; (2) additional uncertainty factors for NBPs with inadequate data; (3) route-specific approaches for assessing exposure; (4) testing with the commercial form of NBPs; (5) initiation of a health surveillance program; and (6) development of educational programs.
Authors:
David Stone; Bryan J Harper; Iseult Lynch; Kenneth Dawson; Stacy L Harper
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of occupational and environmental health     Volume:  16     ISSN:  1077-3525     ISO Abbreviation:  Int J Occup Environ Health     Publication Date:    2010 Oct-Dec
Date Detail:
Created Date:  2011-01-12     Completed Date:  2011-01-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505217     Medline TA:  Int J Occup Environ Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  467-74     Citation Subset:  IM    
Affiliation:
Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA. dave.stone@oregonstate.edu
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MeSH Terms
Descriptor/Qualifier:
Agriculture
Air Pollutants, Occupational / analysis
Environmental Exposure / analysis*
Humans
Nanoparticles / analysis*
Occupational Exposure / analysis
Pesticides / analysis*
Chemical
Reg. No./Substance:
0/Air Pollutants, Occupational; 0/Pesticides
Comments/Corrections
Comment In:
Int J Occup Environ Health. 2010 Oct-Dec;16(4):542-3   [PMID:  21222395 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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