| Exploring violence against women and adverse health outcomes in middle age to promote women's health. | |
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MedLine Citation:
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PMID: 20551737 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A history of intimate partner violence (IPV) is linked to cardiovascular disorders among women. Static autonomic nervous system (ANS) imbalance may result from chronic stress associated with exposure to IPV. Autonomic nervous system imbalance is associated with an excessive proinflammatory response that may increase the risk for inflammatory diseases, including atherosclerosis. To better understand the process from IPV to poorer health outcomes in women diagnosed with acute coronary syndrome (ACS) we developed and tested a biobehavioral model of the psychological and biological pathway from IPV to chronic illness. We hypothesized that among women hospitalized for ACS, those who reported sexual abuse, with or without physical abuse, would have greater alterations in their serum levels of neuroendocrine markers, proinflammatory cytokines, and cell adhesion molecules and a chemotactic cytokine, at time of hospitalization for ACS, and 3 and 6 months later, than do women with physical abuse only. Participants were 45 women, primarily African American, admitted to a county hospital with a diagnosis of ACS. We evaluated 11 biomarkers and found a moderate group effect size for vascular cell adhesion molecule-1. All others had a small effect size. |
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Authors:
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Lene Symes; Judith McFarlane; Lorraine Frazier; Maria C Henderson-Everhardus; Gayle McGlory; Kathleen Bachtel Watson; Yan Liu; Charles E Rhodes; Ron Cornelis Hoogeveen |
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Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Critical care nursing quarterly Volume: 33 ISSN: 1550-5111 ISO Abbreviation: Crit Care Nurs Q Publication Date: 2010 Jul-Sep |
Date Detail:
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Created Date: 2010-06-16 Completed Date: 2010-10-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8704517 Medline TA: Crit Care Nurs Q Country: United States |
Other Details:
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Languages: eng Pagination: 233-43 Citation Subset: N |
Affiliation:
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College of Nursing, Texas Woman's University, 6700 Fannin St, Houston, TX 77030, USA. lsymes@twu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Coronary Syndrome*
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blood,
etiology Analysis of Variance Autonomic Nervous System Diseases / etiology Biological Markers / blood Case-Control Studies Cytokines / blood Dehydroepiandrosterone / blood Female Health Promotion / organization & administration Humans Hydrocortisone / blood Intercellular Adhesion Molecule-1 / blood Middle Aged Models, Biological* Models, Psychological* Nursing Evaluation Research Prolactin / blood Prospective Studies Spouse Abuse / prevention & control, psychology* Statistics, Nonparametric Stress Disorders, Post-Traumatic / etiology Vascular Cell Adhesion Molecule-1 / blood Women's Health |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Cytokines; 0/Vascular Cell Adhesion Molecule-1; 126547-89-5/Intercellular Adhesion Molecule-1; 50-23-7/Hydrocortisone; 53-43-0/Dehydroepiandrosterone; 9002-62-4/Prolactin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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