Document Detail

Exploring time series retrieved from cardiac implantable devices for optimizing patient follow-up.
MedLine Citation:
PMID:  18838359     Owner:  NLM     Status:  MEDLINE    
Current cardiac implantable devices (IDs) are equipped with a set of sensors that can provide useful information to improve patient follow-up and prevent health deterioration in the postoperative period. In this paper, data obtained from an ID with two such sensors (a transthoracic impedance sensor and an accelerometer) are analyzed in order to evaluate their potential application for the follow-up of patients treated with a cardiac resynchronization therapy (CRT). A methodology combining spatiotemporal fuzzy coding and multiple correspondence analysis (MCA) is applied in order to: 1) reduce the dimensionality of the data and provide new synthetic indexes based on the "factorial axes" obtained from MCA; 2) interpret these factorial axes in physiological terms; and 3) analyze the evolution of the patient's status by projecting the acquired data into the plane formed by the first two factorial axes named "factorial plane." In order to classify the different evolution patterns, a new similarity measure is proposed and validated on the simulated datasets, and then, used to cluster observed data from 41 CRT patients. The obtained clusters are compared with the annotations on each patient's medical record. Two areas on the factorial plane are identified, one being correlated with a health degradation of patients and the other with a stable clinical state.
Marie Guéguin; Emmanuel Roux; Alfredo I Hernández; Fabienne Porée; Philippe Mabo; Laurence Graindorge; Guy Carrault
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  IEEE transactions on bio-medical engineering     Volume:  55     ISSN:  1558-2531     ISO Abbreviation:  IEEE Trans Biomed Eng     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-07     Completed Date:  2008-12-18     Revised Date:  2013-06-05    
Medline Journal Info:
Nlm Unique ID:  0012737     Medline TA:  IEEE Trans Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2343-52     Citation Subset:  IM    
INSERM U642, Rennes, France.
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MeSH Terms
Aged, 80 and over
Cardiac Pacing, Artificial*
Cardiography, Impedance
Cluster Analysis
Disease Progression
Heart Conduction System / physiopathology
Heart Failure / therapy
Middle Aged
Monitoring, Physiologic / methods*
Pacemaker, Artificial
Pattern Recognition, Automated / methods*
Principal Component Analysis / methods
Prostheses and Implants
Signal Processing, Computer-Assisted*
Treatment Outcome
Ventricular Dysfunction, Left / therapy
Weights and Measures

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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