Document Detail


Exploring permeability of Escherichia coli competence using quantum dots as fluorescent probes.
MedLine Citation:
PMID:  15571775     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Though people had recognized the pivotal function of CaCl(2) during DNA transformation into Escherichia coli, the mechanism of divalent Ca(2+) cation inducing E. coli competence development is still unknowable. Quantum dots (QDs), as a new fluorescent probe, being applied in biology research, had aroused great interest. We explored the penetrability of E. coli competent cells membrane using QDs and proved directly that competent cells were more permeable than that of noncompetent. The results are significant on understanding the problems of the microbiological genetics.
Authors:
Li Wenhua; Xie Haiyan; Xie Zhixiong; Ou Jianhong; Chen Xiangdong; Shen Ping
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of biochemical and biophysical methods     Volume:  61     ISSN:  0165-022X     ISO Abbreviation:  J. Biochem. Biophys. Methods     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-12-01     Completed Date:  2005-04-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7907378     Medline TA:  J Biochem Biophys Methods     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  265-70     Citation Subset:  IM    
Affiliation:
College of Life Sciences, Wuhan University, Wuhan 430072, PR China.
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MeSH Terms
Descriptor/Qualifier:
Calcium / pharmacology*
Cell Membrane Permeability / drug effects*
Escherichia coli / cytology,  drug effects,  genetics*,  metabolism*
Fluorescent Dyes
Microscopy, Fluorescence / methods*
Plasmids / administration & dosage,  pharmacokinetics*
Quantum Dots*
Spectrometry, Fluorescence / methods
Transformation, Bacterial / genetics
Chemical
Reg. No./Substance:
0/Fluorescent Dyes; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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