Document Detail


Exploring the effect of sialic acid orientation on ligand-receptor interactions.
MedLine Citation:
PMID:  22699370     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Here, we present the synthesis of two sialo-micelles to validate the significance of sialic acid orientation during specific carbohydrate-protein and carbohydrate-carbohydrate interactions. Our data clearly suggest that orientation of carboxylic acid and glycerol side chains of sialic acid moieties exert fine tuning of ligand-receptor interactions.
Authors:
Rohan Yadav; Raghavendra Kikkeri
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-15
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Indian Institute of Science Education and Research, Sai Trinity Building, Pashan, Pune 411021, India. rkikkeri@iiserpune.ac.in.
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