Document Detail


Exploring the Unique Reactivity of Diazoesters: An Efficient Approach to Chiral β-Amino Acids.
MedLine Citation:
PMID:  23323996     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The development of a highly stereospecific process for the C-O to C-N exchange with retention of configuration is described. This transformation enables access to optically enriched β-amido-α-diazoesters. These products are transformed to β-amino acids not readily accessible using known methods.
Authors:
Barry M Trost; Sushant Malhotra; Pascal Ellerbrock
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-16
Journal Detail:
Title:  Organic letters     Volume:  -     ISSN:  1523-7052     ISO Abbreviation:  Org. Lett.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Chemistry, Stanford University , Stanford, California 94305-5080, United States.
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