Document Detail


Experimental study of ureteral calculus disease: effects of calculus size, obstruction and hydration.
MedLine Citation:
PMID:  6632117     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A chronic canine model was developed to study the immediate mechanical effects of ureteral calculi. Totally implanted nephrostomy tubes were used to measure renal pelvic pressure and optical sensors recorded ureteral activity. Surrogate calculi were inserted in a retrograde fashion via a trigonal vesicostomy. Complete obstruction was more common with larger calculi and these all passed spontaneously, by which time ureteral activity had ceased. Reduction in urine output delayed the rise in renal pressure and thus prolonged the time the calculus was retained in the ureter. If large calculi, which normally obstruct, had holes drilled in them to allow free urine flow they remained in the ureter for at least 2 hours and had to be extracted. Therefore, in the first few hours increased proximal hydrostatic pressure was the most important factor responsible for the spontaneous passage of obstructing calculi.
Authors:
C B Algood; N Sood; T Fairchild; M E Mayo
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of urology     Volume:  130     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  999-1004     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Dogs
Female
Hydrostatic Pressure
Kidney Pelvis / physiopathology
Muscle Contraction
Muscle, Smooth / physiopathology
Pressure
Time Factors
Ureter / physiopathology
Ureteral Calculi / etiology,  physiopathology*
Ureteral Obstruction / etiology
Urination
Grant Support
ID/Acronym/Agency:
2 RO1 AM20671-03A1/AM/NIADDK NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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