Document Detail

Experimental study of the formation of the heart tube in the chick embryo.
MedLine Citation:
PMID:  50396     Owner:  NLM     Status:  MEDLINE    
A study was made of the development of the heart tube beginning from Hamburger & Hamilton (1951) stage 8+ up to stage 12. We used labelling with particles of iron oxide followed with time-lapse cinemicrophotography, staining with methylene blue, serial section and cutting the embryo in two halves. Our results led to the conclusion that the tubular heart is formed by the addition of precardiac material into its posterior end, but in addition it is necessary to consider the fusion of the myocardium in a cephalic direction, starting with the fusion of both heart primordia at the rostral end. By this fusion the most anterior part of the heart up to stage 12 is formed.
C Argüello; M V de la Cruz; C S Gómez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of embryology and experimental morphology     Volume:  33     ISSN:  0022-0752     ISO Abbreviation:  J Embryol Exp Morphol     Publication Date:  1975 Feb 
Date Detail:
Created Date:  1975-11-08     Completed Date:  1975-11-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7906439     Medline TA:  J Embryol Exp Morphol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1-11     Citation Subset:  IM    
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MeSH Terms
Chick Embryo*
Heart / embryology*
Methylene Blue
Motion Pictures as Topic
Staining and Labeling
Time Factors
Reg. No./Substance:
61-73-4/Methylene Blue; 7439-89-6/Iron

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