| Experimental sensitivity study of inductive phase shift spectroscopy as non-invasive method for hypoperfusion vs bleeding volumetric detection in brain. | |
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MedLine Citation:
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PMID: 19162746 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hypoperfusion and bleeding in brain are medical conditions that involve a decrease and an increase of the relative amount of blood in tissue respectively. Both pathologies result in brain edema. This study evaluates experimentally the sensitivity of an induction based non-invasive technique for detection of changes of fluid volume through phase shift measurements as a possible method to distinguish brain hypoperfusion and bleeding process by volumetric monitoring. An induction coil-spherical head model was build and tested. The model involves two different diameter coils coaxially centered on a two-compartment glass sphere head model centrally placed with respect to the coils. Fluid volumes of physiological saline in 1 ml decrement and increments were used to simulate different hypoperfusion and bleeding levels respectively. Inductive phase shift measurements were measured in a whole bandwidth (1 kHz-1 GHz) by an experimental inductive spectrometer. The results show significant phase shift increase as a function of frequency and fluid volume in both pathologies simulated. At certain frequencies the hypoperfusion and bleeding phase shifts increase run in opposite ways. The experiments suggest that the tested technique has the potential to distinguish the processes of hypoperfusion and bleeding in brain by non-invasive, continuous and volumetric monitoring. |
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Authors:
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Omar Flores; Boris Rubinsky; César A González |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference Volume: 2008 ISSN: 1557-170X ISO Abbreviation: Conf Proc IEEE Eng Med Biol Soc Publication Date: 2008 |
Date Detail:
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Created Date: 2009-02-16 Completed Date: 2009-05-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101243413 Medline TA: Conf Proc IEEE Eng Med Biol Soc Country: United States |
Other Details:
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Languages: eng Pagination: 678-81 Citation Subset: IM |
Affiliation:
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Unidad Profesional Interdisciplinaria de Ingenieria y Tecnologia Avanzadas-IPN, Mexico DF 07340, Mexico. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Volume* Blood Volume Determination / methods* Brain Ischemia / diagnosis*, physiopathology* Cerebral Hemorrhage / diagnosis*, physiopathology* Diagnosis, Differential Equipment Design Equipment Failure Analysis Humans Magnetics / instrumentation* Plethysmography, Impedance / instrumentation, methods* Reproducibility of Results Sensitivity and Specificity Spectrum Analysis / methods Transducers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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