Document Detail

Experimental reproduction of leprosy in seven-banded armadillos (Dasypus hybridus).
MedLine Citation:
PMID:  3910749     Owner:  NLM     Status:  MEDLINE    
Four autochthonous seven-banded armadillos (Dasypus hybridus) from Argentina which developed disseminated leprosy are reported. The average time from inoculation to death was 14.6 months. Acid-fast bacilli (AFB) were found in the skin, nerves, spleen, lymph nodes, lungs, meninges, and striated muscle. Several tests were used to prove that the AFB found in the infected animals were Mycobacterium leprae: a) failure to grow in standard culture media for mycobacteria, b) extraction of acid-fastness with the pyridine test, c) patterns of growth in the mouse foot pad, and d) histopathologic features.
L M Baliña; R P Valdez; M de Herrera; H Costa Cordova; J Bellocq; N Garcia
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association     Volume:  53     ISSN:  0148-916X     ISO Abbreviation:  Int. J. Lepr. Other Mycobact. Dis.     Publication Date:  1985 Dec 
Date Detail:
Created Date:  1986-03-26     Completed Date:  1986-03-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8505819     Medline TA:  Int J Lepr Other Mycobact Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  595-9     Citation Subset:  IM    
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MeSH Terms
Leprosy / microbiology,  pathology*
Muscles / pathology
Mycobacterium leprae / growth & development
Peripheral Nerves / pathology
Skin / pathology
Time Factors
Xenarthra / microbiology*

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