Document Detail

Experimental renal and hepatic artery embolization with a new embolic agent, atelocollagen, in a porcine model.
MedLine Citation:
PMID:  23266969     Owner:  NLM     Status:  Publisher    
PURPOSE : We aimed to investigate the potentiality of atelocollagen, a new embolic agent which is collagen type I in a porcine experimental model. MATERIALS AND METHODS : Three pigs underwent transcatheter embolization of lower interlobular arteries of the renal artery (n=6) and one branch of the hepatic artery (n=3) with collagen type I. Angiography was performed prearterial, during, and postarterial embolization. After the procedure, samples from the embolized organs were evaluated by histological analysis. RESULTS : Six lower interlobular renal arteries and three hepatic arteries were successfully embolized by administration of 0.8±0.3 mL and 2.9±1.2 mL, respectively, of the collagen type I. Histological findings of the embolized kidney specimens showed that the collagenous materials filled the arterial lumen, whose size ranged from 2.02 to 839.82 μm and reached the level of afferent arteries of glomerular tufts. Although the area of occluded arteries of the liver was smaller than the kidney, histological findings of the liver specimens showed that the collagenous materials filled small arterial lumens from 2.81 to 187.86 μm in diameter. CONCLUSION : Atelocollagen, a collagen type I, has the potential to be used to embolize the distal vessels of both renal and hepatic arteries.
Baba Yasutaka; Hayashi Sadao; Ikeda Shunichiro; Higashi Michiyo; Nakajo Masayuki
Related Documents :
1156819 - Fibrinogen uptake scanning for diagnosis of deep vein thrombosis: a plea for standardiz...
11083299 - Venous thrombosis after acute spinal cord injury: cost analysis of prophylaxis guidelines.
22045089 - Guideliner catheter facilitated pci - a novel device with multiple applications.
8750049 - Deep dorsal vein arterialization in arteriogenic impotence: use of the dorsal artery as...
7633989 - Colour doppler ultrasound in diagnosing venous insufficiency. a comparison to descendin...
8371419 - Can a venous patch graft be a substitute for the tunica albuginea of the penis?
11968719 - Acute aortic dissection involving an aberrant right subclavian artery.
6778169 - Percutaneous transluminal angioplasty: iliac and deep femoral arteries.
23047219 - Bilateral origin of ovarian arteries from accessory renal arteries.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-21
Journal Detail:
Title:  Diagnostic and interventional radiology (Ankara, Turkey)     Volume:  -     ISSN:  1305-3612     ISO Abbreviation:  Diagn Interv Radiol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101241152     Medline TA:  Diagn Interv Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Radiology, Kagoshima University, Kagoshima, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The value of diffusion-weighted imaging and apparent diffusion coefficient quantification in the dia...
Next Document:  Comparison of standardized uptake values obtained from two- and three-dimensional modes of fluorine-...