Document Detail


Experimental reflux esophagitis in rats. A scanning electron-microscopic investigation.
MedLine Citation:
PMID:  2316335     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We investigated the morphological alterations of the esophageal mucosa due to reflux disease by scanning electron microscopy. The esophagi of several rats were perfused with hydrochloric acid in the lower third, which was sealed towards the cardia with an inflatable catheter. Our findings indicate extensive erosion of the esophageal mucosa with detachment of the epithelial layer and underlying lamina propria from the lamina muscularis mucosae. The esophagi of control animals were perfused with physiologic saline solution and displayed no evidence of erosion or ulcerous alterations.
Authors:
S Aharinejad; P Franz; M Fakhari
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta anatomica     Volume:  137     ISSN:  0001-5180     ISO Abbreviation:  Acta Anat (Basel)     Publication Date:  1990  
Date Detail:
Created Date:  1990-04-23     Completed Date:  1990-04-23     Revised Date:  2007-07-02    
Medline Journal Info:
Nlm Unique ID:  0370272     Medline TA:  Acta Anat (Basel)     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  180-3     Citation Subset:  IM    
Affiliation:
1st Department of Anatomy, University of Vienna, Austria.
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MeSH Terms
Descriptor/Qualifier:
Animals
Esophagitis, Peptic / pathology*
Esophagus / ultrastructure
Female
Male
Microscopy, Electron, Scanning
Mucous Membrane / ultrastructure
Rats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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