Document Detail

Experimental quantification of the transmission of Porcine reproductive and respiratory syndrome virus.
MedLine Citation:
PMID:  17479780     Owner:  NLM     Status:  MEDLINE    
We conducted an experiment to determine the ability of vaccine against Porcine reproductive and respiratory syndrome virus (PRRSV) to reduce the transmission of PRRSV among pigs. At the end of the experiment, transmission rates did not differ significantly (P = 0.61) between the vaccinated and nonvaccinated pigs, the mean R-values being 0.598 (95% confidence interval [CI] 0.136 to 3.218) and 0.264 (95% CI 0.008 to 2.266), respectively. The unusually low rate of PRRSV transmission in both groups may not have provided a sufficient challenge to detect a vaccine effect. Several factors could affect the rate of PRRSV transmission: isolate virulence, inoculation dose, inoculation route, number of passages of the challenge virus in cell culture, and population size. Of these, isolate virulence appears to be the most important factor associated with the low transmissibility observed in this study. More studies comparing rates of transmission between PRRSV isolates with diverse levels of virulence are needed to better understand this association.
Enrique Mondaca-Fernández; Tom Meyns; Claudia Muñoz-Zanzi; Carlos Trincado; Robert B Morrison
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire     Volume:  71     ISSN:  0830-9000     ISO Abbreviation:  Can. J. Vet. Res.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-05-07     Completed Date:  2007-06-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8607793     Medline TA:  Can J Vet Res     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  157-60     Citation Subset:  IM    
Swine Disease Eradication Center, College of Veterinary Medicine, University of Minnesota, St. Paul 55108, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Dose-Response Relationship, Immunologic
Population Density
Porcine Reproductive and Respiratory Syndrome* / prevention & control,  transmission,  virology
Porcine respiratory and reproductive syndrome virus / pathogenicity*
Random Allocation
Species Specificity
Time Factors
Viral Vaccines / administration & dosage,  immunology*
Reg. No./Substance:
0/Viral Vaccines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Acute interstitial pneumonia in feedlot cattle: effects of feeding feather meal or vitamin E.
Next Document:  Learning style preferences of undergraduate nursing students.