Document Detail


Experimental pancreatitis in the rat. Changes in pulmonary phospholipids during sodium taurocholate-induced acute pancreatitis.
MedLine Citation:
PMID:  6856989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute haemorrhagic pancreatitis was induced in rats by injecting aqueous solution of sodium taurocholate into the common biliopancreatic duct. Lecithin and lysolecithin were separated from pulmonary homogenate by thin layer chromatography and quantified by phosphorus determination. The ratio of lysolecithin to lecithin increased after the sodium taurocholate injection as well as after i.v. administration of porcine pancreatic phospholipase A2. It was concluded that phospholipase A2, released from pancreatic acinar cells into blood, may convert pulmonary lecithin into lysolecithin during acute pancreatitis. Destruction of pulmonary surfactant may contribute to the development of the adult respiratory distress syndrome as seen in patients suffering from severe acute pancreatitis.
Authors:
H J Aho; R A Ahola; A M Tolvanen; T J Nevalainen
Related Documents :
1796049 - Intrinsic lymphatic partition rate of mepitiostane, epitiostanol, and oleic acid absorb...
24855549 - Derivation, expansion and characterization of clinical grade mesenchymal stem cells fro...
3749809 - Peritoneal blood flow during acute experimental pancreatitis. the role of peritoneal ex...
23041509 - Morphological evaluation of the cerebral blood vessels in the late gestation fetal shee...
22292919 - Efficiency and safety of bipolar vessel and tissue sealing in visceral surgery.
11787559 - The development of blood and lymph vessels of human parathyroid glands in embryonal, fe...
14664199 - Clinical application of a hemoglobin-based oxygen-carrying solution.
5503509 - The penetration of inulin, sucrose, mannitol and tritiated water from the interstitial ...
9168219 - Comparison of accuracy and cost of disposable, nonmechanical pumps used for epidural in...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie     Volume:  182     ISSN:  0300-9130     ISO Abbreviation:  Res Exp Med (Berl)     Publication Date:  1983  
Date Detail:
Created Date:  1983-07-15     Completed Date:  1983-07-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0324736     Medline TA:  Res Exp Med (Berl)     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  79-84     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acute Disease
Animals
Female
Lung / analysis*
Lysophosphatidylcholines / analysis
Pancreatitis / chemically induced,  metabolism*
Phosphatidylcholines / analysis
Phospholipases A / toxicity
Phospholipases A2
Phospholipids / analysis*
Rats
Rats, Inbred Strains
Taurocholic Acid
Chemical
Reg. No./Substance:
0/Lysophosphatidylcholines; 0/Phosphatidylcholines; 0/Phospholipids; 81-24-3/Taurocholic Acid; EC 3.1.1.-/Phospholipases A; EC 3.1.1.4/Phospholipases A2

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Identification of glucocorticoid receptors in normal and neoplastic adult human lung.
Next Document:  Duration of immunity and absorption of cysticerci in calves after treatment of Taenia saginata cysti...