Document Detail


Experimental models of kidney tumors.
MedLine Citation:
PMID:  8423194     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We here present in outline some outstanding results on the animal models of renal tumors submitted to the highest attention, which include two kinds of epithelial neoplasms: those developed from the epithelium lining each the renal tubules (renal cell tumors) and pelvis; the mesenchymal tumor of rat; and tumors with embryonal appearance: the nephroblastoma as well as the variant of it known as the estrogen-induced tumor in the hamster. The review deals with methods for tumor induction and the pathobiology of tumors, the latter mainly focused on the identification of the precise types of renal cells committed in tumor origin. The existence of closely related counterparts of these animal tumors in man is also emphasized, by representing a situation of great potentiality, already exploited, to improve understanding of both the nature and development of renal tumors in man.
Authors:
E Nogueira; A Cardesa; U Mohr
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Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  Journal of cancer research and clinical oncology     Volume:  119     ISSN:  0171-5216     ISO Abbreviation:  J. Cancer Res. Clin. Oncol.     Publication Date:  1993  
Date Detail:
Created Date:  1993-02-24     Completed Date:  1993-02-24     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7902060     Medline TA:  J Cancer Res Clin Oncol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  190-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cricetinae
Disease Models, Animal*
Kidney Neoplasms / etiology*
Rabbits
Rats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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