| Experimental model of laryngotracheal stenosis in infants: effects of different high-frequency jet ventilation patterns on pulmonary parameters. | |
| | |
MedLine Citation:
|
PMID: 21410827 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Background: Supraglottic high-frequency jet ventilation (HFJV) in laryngotracheal surgery in infants with modified jet laryngoscopes offers the surgeon an unimpaired operating field. However, supraglottic HFJV is associated with the development of high airway pressures, inadvertent positive end-expiratory pressure (PEEP) levels, and barotrauma. Methods: We investigated the total lung volumes (TLV) and tidal volume variations at peak inspiratory pressure levels (PIP) and at PEEP levels along with the pulmonary pressures (PIP and PEEP) during two conventional methods of supraglottic HFJV in an infant trachea-lung model without stenosis and with different degrees of stenosis. Results: With augmentation of the driving pressure in the experiment without stenosis, the TLV plus the pulmonary pressures increased. With narrowing of the stenosis, TLV reduced at PIP level and increased at PEEP level. Volume shifts were significantly higher during superimposed HFJV compared with monofrequent HFJV at equivalent stenosis diameter (P < 0.05) except for the setting with 0.3 bar driving pressure (P > 0.05). The pulmonary PIP was in none of the test series higher than 20 mbar, and the pulmonary PEEP did not exceed 14 mbar. Conclusions: The results from our experimental model support the safe and effective clinical use of supraglottic HFJV in infants with tracheal stenosis. Moderate driving pressures provide acceptable pulmonary pressures in normal compliant lungs. |
| | |
Authors:
|
Gerlinde Mausser; Angelika Schellauf; Michael Scherübl; Andreas Arrer; Gerhard Schwarz |
Related Documents
:
|
1888507 - Induced atelectasis of the middle ear and its clinical behavior. 2012577 - The use of the pressure cuff test in the diagnosis of decompression sickness. 438617 - Submucous resection. the treatment of choice in the nose-ear distress syndrome. 2634237 - Separate effects of gravity and venous pressure on regional and capillary blood flows i... 20220517 - Psychosocial determinants of hypertension: laboratory and field models. 10636507 - Smoking, oral contraceptives, and cardiovascular reactivity to stress. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-3-17 |
Journal Detail:
|
Title: Paediatric anaesthesia Volume: - ISSN: 1460-9592 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-3-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9206575 Medline TA: Paediatr Anaesth Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2011 Blackwell Publishing Ltd. |
Affiliation:
|
Division of Anesthesiology for Neurosurgical and Craniofacial Surgery and Intensive Care Medicine, Medical University Graz, Graz, Austria Cand. Med., Medical University Graz, Graz, Austria. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: COMMENTARY: What Lies Beneath.
Next Document: Effect of conjugated estrogen versus conjugated estrogen associated with medroxyprogesterone acetate...