| Experimental microvascular autogenous vein grafts for arterial defects: a study of anastomotic sites. | |
| | |
MedLine Citation:
|
PMID: 3431417 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Autogenous femoral vein grafts with an average external diameter of 1.5 mm and an average length of 2.87 cm have been used to bridge defects in the contralateral femoral artery of 15 adult New Zealand white rabbits. An experimental microvascular technique to minimise trauma to the graft was performed, by which clamps were never applied to the graft itself. Patency was assessed over a 12-week period, and the overall graft success rate, excluding one technical failure, was 86%. Each of the three failures resulted from thrombosis. Histologic examination of the patent anastomoses showed marked medial damage at 1 week, complicated by fibrosis and calcification by 4 weeks; thereafter the intima developed prominent fibroelastic thickening. This led to a degree of luminal narrowing by 12 weeks. However, the underlying medial damage, attributable to operative trauma, did not seem to diminish luminal patency. |
| | |
Authors:
|
A Kruavit; C D Fletcher; P H McKee; B Mayou |
Related Documents
:
|
10536957 - Off-pump arterial grafting: 125 cases using the medtronic-utrecht octopus. 2593797 - Long-term histological changes in 1 millimeter polytetrafluoroethylene (gore-tex) prost... 15793497 - Elective popliteal aneurysms: does venous availability has an impact on indications? 10064367 - The use of biocompound-grafts together with varicose veins. first clinical experience. 23138607 - Management of bicuspid aortic valve with or without involvement of ascending aorta and ... 19666777 - Chronic hypercapnia downregulates arginase expression and activity and increases pulmon... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Microsurgery Volume: 8 ISSN: 0738-1085 ISO Abbreviation: Microsurgery Publication Date: 1987 |
Date Detail:
|
Created Date: 1988-03-07 Completed Date: 1988-03-07 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8309230 Medline TA: Microsurgery Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 201-7 Citation Subset: IM |
Affiliation:
|
Department of Plastic Surgery, St. Thomas's Hospital, London, England. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Arteries / pathology, surgery* Fibrosis Follow-Up Studies Microsurgery* Postoperative Complications Rabbits Thrombosis / etiology Veins / transplantation* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A model for sidewall adhesions in the rabbit: reduction by an absorbable barrier.
Next Document: Experimental models for evaluating antithrombotic therapies in replantation microsurgery.