Document Detail

Experimental gut anastomoses and their revascularization.
MedLine Citation:
PMID:  1101871     Owner:  NLM     Status:  MEDLINE    
A study was made of the healing and revascularization of intestinal anastomoses in the small and large intestines of rabbits. Single-layer and double-layer suture, techniques were used and compared, and revascularization of the anastomoses was particularly examined after devascularization of their distal segments. The anastomotic segments were removed at intervals after construction varying from one to six weeks and studied histologically after haemotoxylin and eosin staining, by xylol-clear thick sections and by angiography, a gelatin Micropaque emulsion being used to fill the vascular network. Forty-four rabbit intestinal anastomoses were studied. Inverted intestinal anastomoses took about two weeks to develop continuous mucosa on the luminal side, and were completely healed after six weeks. Revascularization began after eight days with both single-layer and double-layer anastomoses, proceeding from the submucosal and the surrounding muscular layers. The vascular pattern mirrored the healing stage of the anastomosis. Irregular fine vessels crossing the anastomoses were seen in specimens examined at the second week. After three or four weeks, the vascular patterns of the anastomoses showed an irregularity of calibre and direction because of the presence of residual scar tissue, and the mucosal surfaces were covered with regenerating epithelium. Healing and revascularization were complete after six weeks.
H Nakanishi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Australian and New Zealand journal of surgery     Volume:  45     ISSN:  0004-8682     ISO Abbreviation:  Aust N Z J Surg     Publication Date:  1975 Aug 
Date Detail:
Created Date:  1975-12-28     Completed Date:  1975-12-28     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0373115     Medline TA:  Aust N Z J Surg     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  309-14     Citation Subset:  IM    
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MeSH Terms
Capillaries / physiology
Intestine, Large / blood supply,  physiology,  surgery
Intestine, Small / blood supply,  physiology,  surgery
Intestines / surgery*
Suture Techniques
Wound Healing*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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