Document Detail


Experimental exposure of eggs to polybrominated diphenyl ethers BDE-47 and BDE-99 in red-eared sliders (Trachemys scripta elegans) and snapping turtles (Chelydra serpentina) and possible species-specific differences in debromination.
MedLine Citation:
PMID:  23147837     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Polybrominated diphenyl ethers (PBDEs) are a bioaccumulative, persistent, and toxic class of flame retardants that can potentially impact turtles in natural habitats via exposure through maternal transfer. To simulate maternal transfer in the present study, PBDE congeners BDE-47 and BDE-99 were topically applied to the eggshell and were allowed to diffuse into the egg contents of the red-eared slider (Trachemys scripta elegans) and snapping turtle (Chelydra serpentina). Eggs were topically dosed over 8 d to achieve a target concentration of 40 ng/g in the egg contents. Transfer efficiency was higher for BDE-47 than for BDE-99 in the red-eared sliders (25.8 ± 1.9% vs 9.9 ± 1.1%) and snapping turtles (31.3 ± 1.6% vs 12.5 ± 1.4%), resulting in greater BDE-47 and lower BDE-99 egg content concentrations relative to the 40 ng/g target. However, only 25.8 and 31.3% of the total BDE-47 and 9.9 and 12.5% of the total BDE-99 dose applied could be accounted for in the red-eared slider and snapping turtle egg contents, respectively. Additionally, increased BDE-47 in red-eared slider egg contents dosed with only BDE-99 indicate that BDE-99 might have been debrominated to BDE-47. The efficacy of topical dosing for administering desired embryonic exposures is clearly affected by the chemical properties of the applied compounds and was more successful for BDE-47 in both species.
Authors:
Karen M Eisenreich; Christopher L Rowe
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-12-10
Journal Detail:
Title:  Environmental toxicology and chemistry / SETAC     Volume:  32     ISSN:  1552-8618     ISO Abbreviation:  Environ. Toxicol. Chem.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-17     Completed Date:  2013-07-18     Revised Date:  2013-08-12    
Medline Journal Info:
Nlm Unique ID:  8308958     Medline TA:  Environ Toxicol Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  393-400     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 SETAC.
Affiliation:
University of Maryland Center for Environmental Science, Chesapeake Biological Laboratory, Solomons, Maryland, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Flame Retardants / toxicity*
Halogenated Diphenyl Ethers / toxicity*
Ovum / drug effects*
Polybrominated Biphenyls / toxicity*
Risk Assessment
Species Specificity
Turtles
Water Pollutants, Chemical / toxicity*
Chemical
Reg. No./Substance:
0/2,2',4,4',5-brominated diphenyl ether; 0/Flame Retardants; 0/Halogenated Diphenyl Ethers; 0/Polybrominated Biphenyls; 0/Water Pollutants, Chemical; 0N97R5X10X/2,2',4,4'-tetrabromodiphenyl ether

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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