| Experimental estimation of blood flow velocity through simulation of intravital microscopic imaging in micro-vessels by different image processing methods. | |
| | |
MedLine Citation:
|
PMID: 20659483 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
Quantization of red blood cell (RBC) velocity in micro-vessel is one of the techniques for dynamic observation of microvascular mechanisms. The flow measurement of RBC in micro-vessels is still a challenge nowadays. Image processing for velocity measurement using a frame by frame analysis is a common approach. The accuracy of the calculations, which is algorithm dependant, has rarely been examined. In this paper, we evaluated the accuracy of the existing methods, which includes cross correlation method, Hough transform method, and optical flow method, by applying these methods to simulated micro-vessel image sequences. Simulated experiments in various micro-vessels with random RBC motion were applied in the evaluation. The blood flow variation in the same micro-vessels with different RBC densities and velocities was considered in the simulations. The calculation accuracy of different flow patterns and vessel shapes were also examined, respectively. Based on the comparison, the use of an optical flow method, which is superior to a cross-correlation method or a Hough transform method, is proposed for measuring RBC velocity. The study indicated that the optical flow method is suitable for accurately measuring the velocity of the RBCs in small or large micro-vessels. |
| | |
Authors:
|
Tzung-Chi Huang; Wen-Chen Lin; Chih-Chieh Wu; Geoffrey Zhang; Kang-Ping Lin |
Related Documents
:
|
1066713 - The effect of local anesthetic solutions on the blood vessels of the rat molars. 9547793 - Regulation of cardiovascular collagen deposition by mechanical forces. 8079703 - High cooperativity of hemoglobin-oxygen binding in embryonic rabbit blood. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-07-24 |
Journal Detail:
|
Title: Microvascular research Volume: 80 ISSN: 1095-9319 ISO Abbreviation: Microvasc. Res. Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-11-15 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0165035 Medline TA: Microvasc Res Country: United States |
Other Details:
|
Languages: eng Pagination: 477-83 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Biomedical Imaging and Radiological Science, China Medical University, Taiwan. tzungchi.huang@mail.cmu.edu.tw |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: VEGF-A loss in the haematopoietic and endothelial lineages exacerbates age-induced renal changes.
Next Document: Hyperaemic changes in forearm skin perfusion and RBC concentration after increasing occlusion times.