| Experimental confirmation of potential swept source optical coherence tomography performance limitations. | |
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MedLine Citation:
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PMID: 19023378 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Optical coherence tomography (OCT) has demonstrated considerable potential for a wide range of medical applications. Initial work was done in the time domain OCT (TD-OCT) approach, but recent interest has been generated with spectral domain OCT (SD-OCT) approaches. While SD-OCT offers higher data acquisition rates and no movable parts, we recently pointed out theoretical inferior aspects to its performance relative to TD-OCT. In this paper we focus on specific limitations of swept source OCT (SS-OCT), as this is the more versatile of the two SD-OCT embodiments. We present experimental evidence of reduced imaging penetration, increased low frequency noise, higher multiple scattering (which can be worsened still via aliasing), increased need to control the distance from the sample, and saturation of central bandwidth frequencies. We conclude that for scenarios where the dynamic range is relatively low (e.g., retina), the distance from the sample is relatively constant, or high acquisition rates are needed, SS-OCT has a role. However, when penetration remains important in the setting of a relatively high dynamic range, acquisition rates above video rate are not needed, or the distance to the tissue is not constant, TD-OCT may be the superior approach. |
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Authors:
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Kathy Zheng; Bin Liu; Chuanyong Huang; Mark E Brezinski |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Applied optics Volume: 47 ISSN: 1539-4522 ISO Abbreviation: Appl Opt Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-21 Completed Date: 2009-01-23 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0247660 Medline TA: Appl Opt Country: United States |
Other Details:
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Languages: eng Pagination: 6151-8 Citation Subset: IM |
Affiliation:
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Center for Optical Coherence Tomography and Optical Physics, Department of Orthopedic Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms* Animals Cattle Image Enhancement / methods Image Interpretation, Computer-Assisted / methods* Imaging, Three-Dimensional / methods* Lighting / methods* Menisci, Tibial / cytology* Reproducibility of Results Sensitivity and Specificity Tomography, Optical Coherence / methods* |
| Grant Support | |
ID/Acronym/Agency:
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R01 AR044812-10/AR/NIAMS NIH HHS; R01 AR046996-07/AR/NIAMS NIH HHS; R01 AR44812/AR/NIAMS NIH HHS; R01 AR46996/AR/NIAMS NIH HHS; R01 EB000419/EB/NIBIB NIH HHS; R01 EB002638-07/EB/NIBIB NIH HHS; R01 EB02638/HL63953/EB/NIBIB NIH HHS; R01 HL55686/HL/NHLBI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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