Document Detail

Experimental comparison of high-density scintillators for EMCCD-based gamma ray imaging.
MedLine Citation:
PMID:  22722678     Owner:  NLM     Status:  Publisher    
Detection of x-rays and gamma rays with high spatial resolution can be achieved with scintillators that are optically coupled to electron-multiplying charge-coupled devices (EMCCDs). These can be operated at typical frame rates of 50 Hz with low noise. In such a set-up, scintillation light within each frame is integrated after which the frame is analyzed for the presence of scintillation events. This method allows for the use of scintillator materials with relatively long decay times of a few milliseconds, not previously considered for use in photon-counting gamma cameras, opening up an unexplored range of dense scintillators. In this paper, we test CdWO(4) and transparent polycrystalline ceramics of Lu(2)O(3):Eu and (Gd,Lu)(2)O(3):Eu as alternatives to currently used CsI:Tl in order to improve the performance of EMCCD-based gamma cameras. The tested scintillators were selected for their significantly larger cross-sections at 140 keV ((99m)Tc) compared to CsI:Tl combined with moderate to good light yield. A performance comparison based on gamma camera spatial and energy resolution was done with all tested scintillators having equal (66%) interaction probability at 140 keV. CdWO(4), Lu(2)O(3):Eu and (Gd,Lu)(2)O(3):Eu all result in a significantly improved spatial resolution over CsI:Tl, albeit at the cost of reduced energy resolution. Lu(2)O(3):Eu transparent ceramic gives the best spatial resolution: 65 µm full-width-at-half-maximum (FWHM) compared to 147 µm FWHM for CsI:Tl. In conclusion, these 'slow' dense scintillators open up new possibilities for improving the spatial resolution of EMCCD-based scintillation cameras.
Jan W T Heemskerk; Rob Kreuger; Marlies C Goorden; Marc A N Korevaar; Samuel Salvador; Zachary M Seeley; Nerine J Cherepy; Erik van der Kolk; Stephen A Payne; Pieter Dorenbos; Freek J Beekman
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-22
Journal Detail:
Title:  Physics in medicine and biology     Volume:  57     ISSN:  1361-6560     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401220     Medline TA:  Phys Med Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  4545-4554     Citation Subset:  -    
Radiation, Detection and Medical Imaging, Department of Applied Sciences, Delft University of Technology, Mekelweg 15, 2629 JB, Delft, the Netherlands. Nuclear Medicine Department, University Hospital Vrije Universiteit Brussel, Laarbeeklaan 101, B-1090 Brussels, Belgium.
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