| Experimental comparison of high-density scintillators for EMCCD-based gamma ray imaging. | |
| | |
MedLine Citation:
|
PMID: 22722678 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Detection of x-rays and gamma rays with high spatial resolution can be achieved with scintillators that are optically coupled to electron-multiplying charge-coupled devices (EMCCDs). These can be operated at typical frame rates of 50 Hz with low noise. In such a set-up, scintillation light within each frame is integrated after which the frame is analyzed for the presence of scintillation events. This method allows for the use of scintillator materials with relatively long decay times of a few milliseconds, not previously considered for use in photon-counting gamma cameras, opening up an unexplored range of dense scintillators. In this paper, we test CdWO(4) and transparent polycrystalline ceramics of Lu(2)O(3):Eu and (Gd,Lu)(2)O(3):Eu as alternatives to currently used CsI:Tl in order to improve the performance of EMCCD-based gamma cameras. The tested scintillators were selected for their significantly larger cross-sections at 140 keV ((99m)Tc) compared to CsI:Tl combined with moderate to good light yield. A performance comparison based on gamma camera spatial and energy resolution was done with all tested scintillators having equal (66%) interaction probability at 140 keV. CdWO(4), Lu(2)O(3):Eu and (Gd,Lu)(2)O(3):Eu all result in a significantly improved spatial resolution over CsI:Tl, albeit at the cost of reduced energy resolution. Lu(2)O(3):Eu transparent ceramic gives the best spatial resolution: 65 µm full-width-at-half-maximum (FWHM) compared to 147 µm FWHM for CsI:Tl. In conclusion, these 'slow' dense scintillators open up new possibilities for improving the spatial resolution of EMCCD-based scintillation cameras. |
| | |
Authors:
|
Jan W T Heemskerk; Rob Kreuger; Marlies C Goorden; Marc A N Korevaar; Samuel Salvador; Zachary M Seeley; Nerine J Cherepy; Erik van der Kolk; Stephen A Payne; Pieter Dorenbos; Freek J Beekman |
Related Documents
:
|
22380288 - Novel methods for improvement of a penning ion source for neutron generator applications. 22481178 - Vibrational spectroscopic investigation on the structure of 2-ethylpyridine-4-carbothio... 23453708 - Fabrication and characterization of ii-vi semiconductor nanoparticles decorated electro... 6207058 - 2 cases of hereditary palmoplantar keratoderma. an abnormality of keratohyalin granules... 12730598 - Electrically induced optical emission from a carbon nanotube fet. 17600798 - In silico engineering of tailored ink-binding ability at molecular printboards. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-6-22 |
Journal Detail:
|
Title: Physics in medicine and biology Volume: 57 ISSN: 1361-6560 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
|
Created Date: 2012-6-22 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: - |
Other Details:
|
Languages: ENG Pagination: 4545-4554 Citation Subset: - |
Affiliation:
|
Radiation, Detection and Medical Imaging, Department of Applied Sciences, Delft University of Technology, Mekelweg 15, 2629 JB, Delft, the Netherlands. Nuclear Medicine Department, University Hospital Vrije Universiteit Brussel, Laarbeeklaan 101, B-1090 Brussels, Belgium. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Current Management of Patients with Severe von Willebrand Disease Type 3: A 2012 Update.
Next Document: The Newborn Lamb as A New Model For Studying Gastroesophageal Reflux.