| Experimental colitis does not increase the prevalence of ANKENT, a spontaneous joint disease in mice. | |
| | |
MedLine Citation:
|
PMID: 15881413 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A possible relationship between intestinal inflammation and joint disease development was investigated. Clinical symptoms of colitis--diarrhea and rectal bleeding--were confirmed by findings of inflammatory processes in the colon in dextran sodium sulfate-treated mice and joint ankylosing enthesopathy (ANKENT) developed in 12.8 % mice with chronic colitis and 13.6 % mice in the control group. Consequently no significant difference in ANKENT frequency was found between mice with and without chronic colitis and the occurrence of ANKENT in both groups was typical for conventional conditions. ANKENT cannot be triggered solely a generalized inflammatory process in the gut. |
| | |
Authors:
|
J Capková; R Stepánková; T Hudcovic; J Sinkora; Z Reháková |
Related Documents
:
|
20637203 - Altered macrophage function contributes to colitis in mice defective in the phosphoinos... 15217783 - Relative contributions of nos isoforms during experimental colitis: endothelial-derived... 11160153 - Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Folia microbiologica Volume: 49 ISSN: 0015-5632 ISO Abbreviation: Folia Microbiol. (Praha) Publication Date: 2004 |
Date Detail:
|
Created Date: 2005-05-09 Completed Date: 2005-07-11 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0376757 Medline TA: Folia Microbiol (Praha) Country: Czech Republic |
Other Details:
|
Languages: eng Pagination: 745-50 Citation Subset: IM |
Affiliation:
|
Department of Biology and Biochemistry of Reproduction, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, 142 20 Prague, Czechia. capkova@biomed.cas.cz |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Ankylosis / epidemiology*, etiology Colitis, Ulcerative / chemically induced*, complications*, pathology, physiopathology Colon / pathology Dextran Sulfate / adverse effects Disease Models, Animal Foot Joints / pathology Humans Male Mice Mice, Inbred C57BL Prevalence |
| Chemical | |
Reg. No./Substance:
|
9042-14-2/Dextran Sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Quantitative aspects of lipopolysaccharide and cytokine requirements to generate nitric oxide in mac...
Next Document: Expression of inflammatory markers in pig amnion after intraamniotic infection with nonpathogenic or...