Document Detail

Experimental characterization of a prototype detector system for carbon ion radiography and tomography.
MedLine Citation:
PMID:  23296259     Owner:  NLM     Status:  Publisher    
Ion beams exhibit a finite range and an inverted depth-dose profile, the Bragg peak. These favorable physical properties allow excellent tumor-dose conformality. However, they introduce sensitivity to range uncertainties. Although these uncertainties are typically taken into account in treatment planning, delivery of the intended dose to the patient has to be ensured daily to prevent underdosage of the tumor or overdosage of surrounding critical structures. Thus, imaging techniques play an increasingly important role for treatment planning and in situ monitoring in ion beam therapy. At the Heidelberg Ion Beam Therapy (HIT) center, a prototype detector system based on a stack of 61 ionization chambers has been assembled for the purpose of radiographic and tomographic imaging of transmitted energetic ions. Its applicability to ion-based transmission imaging was investigated experimentally. An extensive characterization of the set-up in terms of beam parameters and settings of the read-out electronics was performed. Overall, the findings of this work support the potential of an efficient experimental set-up as the range telescope equipped with high sensitivity and fast electronics to perform heavy ion radiography and tomography at HIT.
I Rinaldi; S Brons; J Gordon; R Panse; B Voss; O Jäkel; K Parodi
Related Documents :
24562129 - Circular-linear grating talbot interferometry with moiré fresnel imaging for beam coll...
16019199 - Municipal solid waste landfill siting using intelligent system.
23201879 - Synthetic aperture laser optical feedback imaging using a translational scanning with g...
17560309 - Radiological manifestations of sarcoidosis.
18807029 - Haemophilia imaging: a review.
23927099 - Quantitative non-linear ultrasonic imaging of targets with significant acoustic impedan...
24404449 - Classic pneumatosis intestinalis and hepatic portal venous gas in setting of severe abd...
16292959 - Two-dimensional phased arrays of sources and detectors for depth discrimination in diff...
9024349 - Assessment of the lingual nerve in the third molar region using magnetic resonance imag...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-08
Journal Detail:
Title:  Physics in medicine and biology     Volume:  58     ISSN:  1361-6560     ISO Abbreviation:  Phys Med Biol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401220     Medline TA:  Phys Med Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  413-427     Citation Subset:  -    
German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. University Hospital Heidelberg, Im Neuenheimer Feld 400, D-69120 Heidelberg, Germany. Heidelberg Ion Therapy Center, Im Neuenheimer Feld 450, D-69120 Heidelberg, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The Use of a New Gel Foam for the Evaluation of Tubal Patency.
Next Document:  Leptospirosis in New Orleans.