| Experimental branch pulmonary artery stenosis angioplasty using a novel cutting balloon. | |
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MedLine Citation:
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PMID: 9738163 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determined the safety and efficacy of a bladed balloon in the treatment of branch pulmonary artery stenosis, a model of left pulmonary artery stenosis was surgically created in two-week-old pigs. Seven pigs underwent angioplasty, five with the bladed balloon and two with conventional balloons. Overall, acute results showed a fall in the peak systolic pressure gradients from 8.3 +/- 2.3 mmHg to 3.2 +/- 3.1 mmHg and an increase in the minimum stenotic diameters from 4.5 +/- 2mm to 5.6 +/- mm. Acute pathological examination after cutting angioplasty showed regular luminal cuts that healed completely by four to six weeks in chronically surviving animals. Two of three surviving animals had persistent vessel enlargement at follow-up with one showing little overall change. Cutting balloons are effective in branch pulmonary artery angioplasty and may have clinical applications. |
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Authors:
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A G Magee; D Wax; Y Saiki; I Rebekya; L N Benson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Canadian journal of cardiology Volume: 14 ISSN: 0828-282X ISO Abbreviation: Can J Cardiol Publication Date: 1998 Aug |
Date Detail:
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Created Date: 1998-09-24 Completed Date: 1998-09-24 Revised Date: 2008-04-09 |
Medline Journal Info:
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Nlm Unique ID: 8510280 Medline TA: Can J Cardiol Country: CANADA |
Other Details:
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Languages: eng Pagination: 1037-41 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Hospital for Sick Children, University of Toronto School of Medicine, Ontario. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Balloon* Animals Disease Models, Animal Heart Defects, Congenital / diagnosis, therapy* Humans Microscopy, Electron, Scanning Transmission Pulmonary Artery / physiopathology* Pulmonary Valve Stenosis / diagnosis, therapy* Swine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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