Document Detail

Experimental Infection of Koi Carp with Viral Hemorrhagic Septicemia Virus Type IVb.
MedLine Citation:
PMID:  23289973     Owner:  NLM     Status:  In-Data-Review    
Abstract Viral hemorrhagic septicemia virus (VHSV) type IVb has a wide host range that includes at least three cyprinid species: Fathead Minnow Pimephales promelas, Emerald Shiner Notropis atherinoides, and Bluntnose Minnow P. notatus. To date, VHSV IVb has only been found in wild fish. However, the possibility of infection in culture facilities remains. Koi Carp Cyprinus carpio are a major ornamental aquaculture species in the United States; however, their potential to become infected with VHSV IVb has not yet been examined. In this study, we exposed Koi to 3 × 10(6) PFU VHSV Great Lakes isolate MI03 by intraperitoneal injection. While we observed low mortality (0-5%), VHSV was isolated in cell culture from the majority of fish up to 28 d postexposure (DPE) and was detected by a quantitative reverse transcription polymerase chain reaction (qRT-PCR) assay up to 90 DPE, when the trial was terminated. The results of this study strongly suggest that Koi are at risk for VHSV infection, although their susceptibility by intraperitoneal injection appears to be low.  This study also provides more evidence of the sensitivity of qRT-PCR for detection of VHSV IVb. Received May 9, 2012; accepted September 14, 2012.
Emily R Cornwell; Sandra L Labuda; Geoffrey H Groocock; Rodman G Getchell; Paul R Bowser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of aquatic animal health     Volume:  25     ISSN:  0899-7659     ISO Abbreviation:  J. Aquat. Anim. Health     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-01-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9884881     Medline TA:  J Aquat Anim Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  36-41     Citation Subset:  IM    
a Aquatic Animal Health Program, Department of Microbiology and Immunology, College of Veterinary Medicine , Cornell University , Upper Tower Road , Ithaca , New York , 14853 , USA.
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