| Experiment, thermal simulation, and characterizations on transmission laser coating of hydroxyapatite on metal implant. | |
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MedLine Citation:
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PMID: 19165793 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Coating of bioceramic material, Hydroxyapatite (HAp), on metal implant has attracted many attentions in biomedical industry recently because its combination of good mechanical property and biocompatibility. However, most of current HAp coatings lack coating/substrate interfacial strength, and/or biocompatibility. The cell-tissue attachment is affected by the degraded biocompatibility due to decomposition of HAp during high temperature processing. In this article, an innovative method, transmission laser coating (TLC), is investigated to coat HAp on Ti substrate with low temperature processing. This process enhances the HAp/Metal interfacial property of current coatings, while maintaining good biocompatibility. Experiments are conducted using a continuous neodymium-doped yttrium aluminium garnet (Nd-YAG) laser. Multiphysics simulation is conducted to simulate the temperature distribution in coatings and substrates during TLC processing. X-ray energy dispersion spectrum is used to measure the chemical composition of HAp coatings after TLC process. Pull-out tests are conducted to measure the interfacial strength between the HAp coating and Ti substrate. Cell culture study is conducted to qualitatively evaluate the biocompatibility after TLC of HAp particles. These results show that TLC processing will open new ways of producing biocompatible bioceramic coatings with controlled thickness, and at low processing temperature. |
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Authors:
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Gary J Cheng; Chang Ye |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Journal of biomedical materials research. Part A Volume: 92 ISSN: 1552-4965 ISO Abbreviation: J Biomed Mater Res A Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-11-25 Completed Date: 2010-02-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101234237 Medline TA: J Biomed Mater Res A Country: United States |
Other Details:
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Languages: eng Pagination: 70-9 Citation Subset: IM |
Affiliation:
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School of Industrial Engineering, Purdue University, West Lafayette, Indiana 47906, USA. gjcheng@purdue.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adhesiveness
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drug effects Cell Shape / drug effects Cells, Cultured Coated Materials, Biocompatible / pharmacology* Computer Simulation Durapatite / pharmacology* Humans Lasers* Materials Testing / methods* Metals / chemistry* Osteoblasts / cytology, drug effects, ultrastructure Prostheses and Implants* Surface Properties / drug effects Temperature* Titanium / pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Coated Materials, Biocompatible; 0/Metals; 1306-06-5/Durapatite; 7440-32-6/Titanium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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