Document Detail


Experiences in establishing a PEPFAR-supported laboratory quality system in Nigeria.
MedLine Citation:
PMID:  20855634     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The need to accurately diagnose HIV-infected persons and monitor their immune status and sequelae from increased access to antiretroviral therapy dictated the establishment of a quality assurance (QA) system supported by dedicated personnel, financial resources, and a close monitoring system. Assessment of laboratories and personnel in Nigeria revealed the need for improved laboratory infrastructure and training, including on-site didactic and wet workshops and the institution of a tiered QA unit of laboratory regional officers, focal persons, and site monitors who provided guidance and continuous monitoring. Quarterly assessments and generated reports guided corrective actions. A sustainable quality laboratory system was developed for the first time in Nigeria with funding from the US President's Emergency Plan for AIDS Relief. With expansion from 7 to 34 comprehensive treatment sites, a tiered laboratory organizational structure with regional and site-based Nigerian quality control officers was developed. Measured improvements included reduction in deficiencies from 13% to 2%.
Authors:
Alash'le G Abimiku; Talishiea Croxton; Ezekiel Akintunde; Bimpe Okelade; Joseph Jugu; Sam Peters; Patrick Dakum; William Blattner; Niel Constantine
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  134     ISSN:  1943-7722     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-21     Completed Date:  2010-10-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  541-9     Citation Subset:  AIM; IM    
Affiliation:
Institute of Human Virology, University of Maryland School of Medicine, 725 W Lombard St, N449, Baltimore, MD 21201, USA.
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MeSH Terms
Descriptor/Qualifier:
Developing Countries
Female
HIV Infections / diagnosis*,  drug therapy*,  immunology
Humans
International Cooperation
Laboratories / standards*
Laboratory Personnel / education
Laboratory Techniques and Procedures / standards
Male
Nigeria
Quality Assurance, Health Care / organization & administration
Quality Control*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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