Document Detail


Experience with serum alpha-fetoprotein and human chorionic gonadotropin in non-seminomatous testicular tumors.
MedLine Citation:
PMID:  6159485     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Serum levels of alpha-fetoprotein and human chorionic gonadotropin were used in the management of 50 consecutive patients with non-seminomatous germ cell tumors of the testis. Of the 50 patients 36 had clinical or pathologic documentation of malignancy at some time during their treatment and 34 of these patients (94 per cent) had elevated levels of 1 or both of the markers. The marker(s) was elevated before lymphadenectomy in 9 of 15 patients (60 per cent) with clinical stage A or B disease wh had not been cured by orchiectomy. Among patients with pathologic stage B disease elevated marker levels before or after lymphadenectomy were of no prognostic significance. All of the patients with stage C disease had elevated marker(s) and the effectiveness of chemotherapy in destroying measurable disease generally was reflected in the marker levels.
Authors:
J E Fowler; G Taylor; J Blom; R E Stutzman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  124     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1980 Sep 
Date Detail:
Created Date:  1981-01-29     Completed Date:  1981-01-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  365-8     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Castration
Chorionic Gonadotropin / blood*
Dysgerminoma / blood,  surgery
Humans
Lymph Node Excision
Male
Middle Aged
Neoplasm Metastasis
Prognosis
Testicular Neoplasms / blood*,  surgery
alpha-Fetoproteins* / analysis
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/alpha-Fetoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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