Document Detail

Experience with a low profile bipolar, active fixation pacing lead in pediatric patients.
MedLine Citation:
PMID:  10461290     Owner:  NLM     Status:  MEDLINE    
Continued miniaturization of permanent pacing systems has promoted use of this technology in younger and smaller pediatric patients. Intermedics ThinLine 438-10 active fixation pacing leads (4.5 Fr lead body) were implanted in 26 patients (17 males/9 females; 9.9 +/- 6.9 years). Twenty of 26 patients received dual chamber systems, 6 of 26 patients single lead systems. Each patient has been followed 3 months. Pacemaker analysis at implant and 6 months later evaluated pulse width thresholds at 2.5 V (atrial 0.07 +/- 0.02 vs 0.13 +/- 0.02 ms [P = 0.01]; ventricular 0.08 +/- 0.04 ms vs 0.20 +/- 0.04 ms [P = 0.01]); sensing thresholds (atrial 4.1 +/- 0.41 mV vs 4.0 +/- 4.2 mV [P = NS]; ventricular 9.7 +/- 0.72 vs 9.3 +/- 0.94 mV [P = NS]); and impedance (atrial 345 +/- 12 vs 370 +/- 120 O [P = 0.04]; ventricular 412 +/- 17 vs 458 +/- 190 O [P < 0.01]). One volt lead failed with exit block at approximately 6 weeks. The youngest (9 months to 5 years) and smallest (6.5-18.0 kg) ten patients have each shown by venography to have at least mild venous stenosis at the lead(s) insertion site; five patients demonstrated collateral formation around asymptomatic obstruction, with no thrombus formation. The Intermedics 438-10 ThinLine pacing lead has demonstrated good and stable early postimplant electrical parameters. Angiographic evaluation in our smaller patients has shown evidence for asymptomatic venous obstruction.
R M Campbell; A A Raviele; E J Hulse; D O Auld; G J McRae; V K Tam; K R Kanter
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  22     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-10-05     Completed Date:  1999-10-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1152-7     Citation Subset:  IM    
Children's Heart Center at Egleston Scottish Rite, Atlanta, Georgia, USA.
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MeSH Terms
Atrioventricular Node / surgery
Brachiocephalic Veins / radiography,  ultrasonography
Cardiac Pacing, Artificial*
Cardiomyopathy, Hypertrophic / physiopathology,  therapy*,  ultrasonography
Catheter Ablation / adverse effects
Child, Preschool
Electrodes, Implanted
Follow-Up Studies
Heart Block / etiology,  physiopathology,  therapy*,  ultrasonography
Long QT Syndrome / physiopathology,  therapy*,  ultrasonography
Maximum Allowable Concentration
Pacemaker, Artificial / standards*
Prosthesis Implantation
Retrospective Studies
Sick Sinus Syndrome / physiopathology,  therapy*,  ultrasonography
Subclavian Vein / radiography,  ultrasonography
Ultrasonography, Doppler
Vena Cava, Superior / radiography,  ultrasonography

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