| Experience with fibrin seal (Tisseel) in operations for congenital heart defects. | |
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MedLine Citation:
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PMID: 6207785 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tisseel (human fibrin seal) was used in 38 children with complex congenital heart defects (2.8% of all operations for congenital heart defects) between July, 1980, and August, 1983. Control of bleeding was excellent in 31 patients, good in 6 patients, and unsatisfactory in 1 patient. Best results were achieved when Tisseel was applied on collagen substrate. If bleeding was particularly difficult to control, a combination of Tisseel with pharmacological hypotension (sodium nitroprusside) was used. We recommend the use of Tisseel to preseal Dacron conduits and to control bleeding from multiple suture lines (conduits, arterial switch operations, complex reconstructions of the pulmonary arteries), near major coronary arteries, from Gore-Tex patches in high-pressure systems, and from the raw areas of the heart at reoperation. |
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Authors:
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J Stark; M de Leval |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 38 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 1984 Oct |
Date Detail:
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Created Date: 1984-11-16 Completed Date: 1984-11-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 411-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aprotinin* Calcium Chloride* Child Drug Combinations Fibrin Tissue Adhesive Fibrinogen* Heart Defects, Congenital / surgery* Hemostasis, Surgical* Humans Intraoperative Complications Thrombin* Tissue Adhesives* |
| Chemical | |
Reg. No./Substance:
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0/Drug Combinations; 0/Fibrin Tissue Adhesive; 0/Tissue Adhesives; 10043-52-4/Calcium Chloride; 9001-32-5/Fibrinogen; 9087-70-1/Aprotinin; EC 3.4.21.5/Thrombin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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